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Sahil Sharma

  1. "Hematologic Malignancies Research"
Formats
  1. Journal Article (16)
  2. Review (5)
  3. Meeting Abstract (3)
  4. Book Section (1)
  5. Editorial (1)
Groups
  1. Center for Hematologic Malignancies (26)
  2. GSK Faculty (26)
  3. Hematologic Malignancies Research (26)
  4. Molecular Pharmacology and Chemistry Program Faculty (26)
  5. Sloan Kettering Institute Faculty (26)
  6. Sloan Kettering Institute Postdocs (26)

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People
  1. Gabriela Chiosis (26)
  2. Chander Digwal (15)
  3. Palak Panchal (12)
  4. Suhasini Joshi (11)
  5. Tony Taldone (11)
  6. Anna Rodina Balingcongan (9)

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Years
  1. 2025 (1)
  2. 2024 (4)
  3. 2023 (5)
  4. 2022 (2)
  5. 2021 (4)
  6. 2020 (4)

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Publications
  1. Nature Communications (3)
  2. Biomedicines (2)
  3. Blood (2)
  4. ACS Chemical Biology (1)
  5. Biomolecules (1)
  6. Cell Reports (1)

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Publishers
  1. Nature Publishing Group (4)
  2. Cell Press (3)
  3. MDPI (3)
  4. American Society of Hematology (2)
  5. Springer Nature (2)
  6. Wiley Blackwell (2)

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Results (26)

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  • Epichaperomes: Redefining chaperone biology and therapeutic strategies in complex diseases
    Review

    Pasala, C.; Digwal, C. S.; Sharma, S.; Wang, S.; Bubula, A.; Chiosis, G.
    RSC Chemical Biology (2025)

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  • Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferation
    Journal Article

    Roychowdhury, T.; McNutt, S. W.; Pasala, C.; Nguyen, H. T.; Thornton, D. T.; Sharma, S.; Botticelli, L.; Digwal, C. S.; Joshi, S.; Yang, N.; more...
    Nature Communications (2024)

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  • N-glycosylation-induced pathologic protein conformations as a tool to guide the selection of biologically active small molecules
    Journal Article

    Magni, A.; Sciva, C.; Castelli, M.; Digwal, C. S.; Rodina, A.; Sharma, S.; Ochiana, S.; Patel, H. J.; Shah, S.; Chiosis, G.; more...
    Chemistry - A European Journal (2024)

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  • Synthesis and characterization of click chemical probes for single-cell resolution detection of epichaperomes in neurodegenerative disorders
    Journal Article

    Bay, S.; Digwal, C. S.; Rodilla Martín, A. M.; Sharma, S.; Stanisavljevic, A.; Rodina, A.; Attaran, A.; Roychowdhury, T.; Parikh, K.; Toth, E.; more...
    Biomedicines (2024)

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  • N-glycosylation as a modulator of protein conformation and assembly in disease
    Review

    Pasala, C.; Sharma, S.; Roychowdhury, T.; Moroni, E.; Colombo, G.; Chiosis, G.
    Biomolecules (2024)

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  • Unraveling the mechanism of epichaperome modulation by zelavespib: Biochemical insights on target occupancy and extended residence time at the site of action
    Journal Article

    Sharma, S.; Joshi, S.; Kalidindi, T.; Digwal, C. S.; Panchal, P.; Lee, S. G.; Zanzonico, P.; Pillarsetty, N.; Chiosis, G.
    Biomedicines (2023)

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  • Use of native-PAGE for the identification of epichaperomes in cell lines
    Journal Article

    Roychowdhury, T.; Santhaseela, A. R.; Sharma, S.; Panchal, P.; Rodina, A.; Chiosis, G.; Calderwood, S. K.; Prince, T. L.
    Chaperones: Methods and Protocols. 2nd ed (2023)

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  • Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
    Journal Article

    Rodina, A.; Xu, C.; Digwal, C. S.; Joshi, S.; Patel, Y.; Santhaseela, A. R.; Bay, S.; Merugu, S.; Alam, A.; Yan, P.; more...
    Nature Communications (2023)

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  • Epichaperomes as a gateway to understanding, diagnosing, and treating disease through rebalancing protein-protein interaction networks
    Book Section

    Digwal, C. S.; Sharma, S.; Santhaseela, A. R.; Ginsberg, S. D.; Chiosis, G.
    In Kostic, M.; Jones, L. H. (Eds.) Protein Homeostasis in Drug Discovery: A Chemical Biology Perspective (2023)

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  • Targeting stressor-induced dysfunctions in protein–protein interaction networks via epichaperomes
    Editorial

    Ginsberg, S. D.; Sharma, S.; Norton, L.; Chiosis, G.
    Trends in Pharmacological Sciences (2023)

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