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Andrew C Koff

  1. "2018"
Formats
  1. Journal Article (3)
  2. Meeting Abstract (2)
Groups
  1. Alumni (GSK) (5)
  2. Department of Medicine (5)
  3. GSK Faculty (5)
  4. Gerstner Sloan Kettering Graduate School of Biomedical Sciences (5)
  5. MSK Grad Students (5)
  6. Molecular Biology Program Faculty (5)

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People
  1. Mary Klein (5)
  2. William Tap (5)
  3. Aimee Crago (3)
  4. Mark Dickson (3)
  5. Marta Kovatcheva (3)
  6. Samuel Singer (3)

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Years
  1. 2018 (5)
Publications
  1. Annals of Oncology (1)
  2. Cancer Cell (1)
  3. Clinical Cancer Research (1)
  4. Molecular & Cellular Oncology (1)
  5. Oncogene (1)
Publishers
  1. American Association for Cancer Research (1)
  2. Cell Press (1)
  3. Nature Publishing Group (1)
  4. Oxford University Press (1)
  5. Taylor & Francis Group (1)

Results (5)

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  • PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence
    Journal Article

    Klein, M. E.; Dickson, M. A.; Antonescu, C.; Qin, L. X.; Dooley, S. J.; Barlas, A.; Manova, K.; Schwartz, G. K.; Crago, A. M.; Singer, S.; more...
    Oncogene (2018)

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  • CDK4/6 inhibitors: The mechanism of action may not be as simple as once thought
    Journal Article

    Klein, M. E.; Kovatcheva, M.; Davis, L. E.; Tap, W. D.; Koff, A.
    Cancer Cell (2018)

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  • Mechanistic understanding of the role of ATRX in senescence provides new insight for combinatorial therapies with CDK4 inhibitors
    Journal Article

    Kovatcheva, M.; Klein, M. E.; Tap, W. D.; Koff, A.
    Molecular & Cellular Oncology (2018)

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  • Senescence after growth arrest: A mechanism by which CDK4/6 inhibitors can mediate their activity suppressing tumor progression
    Meeting Abstract

    Koff, A.; Klein, M. E.; Dickson, M. A.; Antonescu, C.; Qin, L. X.; Dooley, S. J.; Schwartz, G.; Crago, A. M.; Singer, S.; Tap, W. D.
    Annals of Oncology (2018)

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  • CDK4 inhibition and senescence: Pathway understanding leads to rational drug combinations
    Meeting Abstract

    Klein, M. E.; Kovatcheva, M.; Dickson, M. A.; Liu, D.; Crago, A. M.; Schwartz, G. K.; Tap, W. D.; Singer, S.; Koff, A.
    Clinical Cancer Research (2018)

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