Synapse - Diego Chowell Puente

Results (17)

Improved prediction of immune checkpoint blockade efficacy across multiple cancer types

Journal Article

Chowell, D.; Yoo, S. K.; Valero, C.; Pastore, A.; Krishna, C.; Lee, M.; Hoen, D.; Shi, H.; Kelly, D. W.; Patel, N.; more...
Nature Biotechnology (2022)

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High response rate and durability driven by HLA genetic diversity in patients with kidney cancer treated with lenvatinib and pembrolizumab

Journal Article

Lee, C. H.; DiNatale, R. G.; Chowell, D.; Krishna, C.; Makarov, V.; Valero, C.; Vuong, L.; Lee, M.; Weiss, K.; Hoen, D.; more...
Molecular Cancer Research (2021)

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Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy

Journal Article

Krishna, C.; DiNatale, R. G.; Kuo, F.; Srivastava, R. M.; Vuong, L.; Chowell, D.; Gupta, S.; Vanderbilt, C.; Purohit, T. A.; Liu, M.; more...
Cancer Cell (2021)

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Putative drivers of aggressiveness in TCEB1-mutant renal cell carcinoma: An emerging entity with variable clinical course

Journal Article

DiNatale, R. G.; Gorelick, A. N.; Makarov, V.; Blum, K. A.; Silagy, A. W.; Freeman, B.; Chowell, D.; Marcon, J.; Mano, R.; Sanchez, A.; more...
European Urology Focus (2021)

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Impact of HLA evolutionary divergence on clinical features of patients with aplastic anemia and paroxysmal nocturnal hemoglobinuria

Meeting Abstract

Pagliuca, S.; Gurnari, C.; Chowell, D.; Krishna, C.; Patel, B. J.; Awada, H.; Kerr, C. M.; Kongkiatkamon, S.; Kishtagari, A.; Laframboise, T.; more...
Blood (2020)

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Genetic and environmental determinants of human TCR repertoire diversity

Journal Article

Krishna, C.; Chowell, D.; Gönen, M.; Elhanati, Y.; Chan, T. A.
Immunity & Ageing (2020)

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The immune microenvironment and noantigen landscape of aggressive salivary gland carcinomas differ by subtype

Journal Article

Linxweiler, M.; Kuo, F.; Katabi, N.; Lee, M.; Nadeem, Z.; Dalin, M. G.; Makarov, V.; Chowell, D.; Dogan, S.; Ganly, I.; more...
Clinical Cancer Research (2020)

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Genomic biomarkers of response to lenvatinib/pembrolizumab (Len/Pembro) in patients with advanced renal cell carcinoma

Meeting Abstract

Lee, C. H.; DiNatale, R. G.; Chowell, D.; Krishna, C.; Makarov, V.; Shapnik, N.; Murray, S. J.; Carlo, M. I.; Voss, M. H.; Feldman, D. R.; more...
Journal of Clinical Oncology (2020)

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Evolutionary divergence of HLA class I genotype impacts efficacy of cancer immunotherapy

Journal Article

Chowell, D.; Krishna, C.; Pierini, F.; Makarov, V.; Rizvi, N. A.; Kuo, F.; Morris, L. G. T.; Riaz, N.; Lenz, T. L.; Chan, T. A.
Nature Medicine (2019)

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Genomic biomarkers of response to nivolumab/ipilimumab (nivo/ipi) and nivolumab (nivo) monotherapy in 108 patients with advanced renal cell carcinoma

Meeting Abstract

Lee, C. H.; Di Natale, R. G.; Chowell, D.; Makarov, V.; Redzematovic, A.; Murray, S. J.; Carlo, M. I.; Voss, M. H.; Feldman, D. R.; Motzer, R. J.; more...
Journal of Clinical Oncology (2019)

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