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Kevin Patrick O'Rourke

Formats
  1. Journal Article (13)
  2. Meeting Abstract (7)
Groups
  1. MSK Grad Students (20)
  2. GSK Faculty (14)
  3. Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center (13)
  4. Center for Hematologic Malignancies (13)
  5. Center for Molecular Imaging and Biotechnology (CMIB) (13)
  6. Executive Committee, Center for Hematologic Malignancies (13)

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People
  1. Scott Lowe (12)
  2. Julio Garcia Aguilar (8)
  3. Jinru Shia (7)
  4. Chin-Tung Chen (6)
  5. Jesse Smith (6)
  6. Raphael Pelossof (6)

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Years
  1. 2022 (2)
  2. 2021 (1)
  3. 2020 (2)
  4. 2019 (3)
  5. 2018 (2)
  6. 2017 (3)

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Publications
  1. Bio-protocol (2)
  2. Cancer Research (2)
  3. Journal of Clinical Oncology (2)
  4. Molecular Biology of the Cell (2)
  5. Molecular Cancer Research (2)
  6. Nature Biotechnology (2)

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Publishers
  1. American Association for Cancer Research (4)
  2. Nature Publishing Group (4)
  3. American Society of Clinical Oncology (2)
  4. Bio-protocol (2)
  5. The American Society for Cell Biology (2)
  6. Cell Press (1)

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Results (20)

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  • KRAS mutants upregulate integrin β4 to promote invasion and metastasis in colorectal cancer
    Journal Article

    Choi, S. H.; Kim, J. K.; Chen, C. T.; Wu, C.; Marco, M. R.; Barriga, F. M.; O'Rourke, K.; Pelossof, R.; Qu, X.; Chang, Q.; more...
    Molecular Cancer Research (2022)

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  • A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets
    Journal Article

    Li, X.; Huang, C. H.; Sánchez-Rivera, F. J.; Kennedy, M. C.; Tschaharganeh, D. F.; Morris, J. P. 4th; Montinaro, A.; O'Rourke, K. P.; Banito, A.; Wilkinson, J. E.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2022)

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  • KRAS mutant rectal cancer cells interact with surrounding fibroblasts to deplete the extracellular matrix
    Journal Article

    Kim, J. K.; Marco, M. R.; Choi, S. H.; Qu, X.; Chen, C. T.; Elkabets, M.; Fairchild, L.; Chow, O.; Barriga, F. M.; Dow, L. E.; more...
    Molecular Oncology (2021)

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  • L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer
    Journal Article

    Ganesh, K.; Basnet, H.; Kaygusuz, Y.; Laughney, A. M.; He, L.; Sharma, R.; O'Rourke, K. P.; Reuter, V. P.; Huang, Y. H.; Turkekul, M.; more...
    Nature Cancer (2020)

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  • L1CAM defines the regenerative origin of metastasis initiating cells in colorectal cancer
    Meeting Abstract

    Ganesh, K.; Basnet, H.; Kaygusuz, Y.; Laughney, A.; He, L.; Sharma, R.; O'Rourke, K.; Reuter, V.; Huang, Y. H.; Masilionis, I.; more...
    Cancer Research (2020)

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  • A rectal cancer organoid platform to study individual responses to chemoradiation
    Journal Article

    Ganesh, K.; Wu, C.; O’Rourke, K. P.; Szeglin, B. C.; Zheng, Y.; Sauvé, C. E. G.; Adileh, M.; Wasserman, I.; Marco, M. R.; Kim, A. S.; more...
    Nature Medicine (2019)

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  • KRAS mutation is associated with upregulation of integrin beta-4 expression leading to tumor invasion in colorectal cancer
    Meeting Abstract

    Choi, S. H.; Marco, M.; Chen, C. T.; Pelossof, R.; O'Rourke, K. P.; Smith, J. J.; Garcia-Aguilar, J.
    Journal of Clinical Oncology (2019)

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  • KRAS mutation is associated with upregulation of integrin ß4 and colorectal cancer invasiveness
    Meeting Abstract

    Choi, S.; Marco, M.; Chen, C.; Pelossof, R.; O'Rourke, K.; Smith, J. J.; Garcia-Aguilar, J.
    Annals of Surgical Oncology (2019)

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  • Regenerative origin of colorectal metastasis stem cells
    Meeting Abstract

    Ganesh, K.; Basnet, H.; O'Rourke, K. P.; Laughney, A. M.; He, L.; Batlle, E.; Lowe, S. W.; Pe'er, D.; Shia, J.; Massague, J.
    Cancer Research (2018)

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  • A genome-wide microRNA screen identifies regulators of tetraploid cell proliferation
    Journal Article

    Vittoria, M. A.; Shenk, E. M.; O’Rourke, K. P.; Bolgioni, A. F.; Lim, S.; Kacprzak, V.; Quinton, R. J.; Ganem, N. J.
    Molecular Biology of the Cell (2018)

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