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Sumit Middha

  1. "Gastrointestinal Oncology Service"
Formats
  1. Journal Article (16)
  2. Meeting Abstract (7)
Groups
  1. Department of Medicine (23)
  2. Gastrointestinal Oncology Service (23)
  3. Solid Tumor Oncology Division (23)
  4. Department of Pathology and Laboratory Medicine (22)
  5. GSK Faculty (21)
  6. Human Oncology and Pathogenesis Program (20)

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People
  1. Jaclyn Hechtman (20)
  2. Ahmet Zehir (17)
  3. Jinru Shia (17)
  4. Marc Ladanyi (14)
  5. Michael Berger (14)
  6. Rona Yaeger (14)

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Years
  1. 2020 (1)
  2. 2019 (6)
  3. 2018 (6)
  4. 2017 (5)
  5. 2016 (5)
Publications
  1. Journal of Clinical Oncology (5)
  2. Modern Pathology (3)
  3. Cancer Research (2)
  4. Journal of Molecular Diagnostics (2)
  5. Molecular Cancer Research (2)
  6. Cancer Cell (1)

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Publishers
  1. American Society of Clinical Oncology (6)
  2. American Association for Cancer Research (5)
  3. Nature Research (3)
  4. Elsevier Science, Inc. (2)
  5. American Association for the Advancement of Science (1)
  6. Cell Press (1)

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Results (23)

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  • Retained mismatch repair protein expression occurs in approximately 6% of microsatellite instability-high cancers and is associated with missense mutations in mismatch repair genes
    Journal Article

    Hechtman, J. F.; Rana, S.; Middha, S.; Stadler, Z. K.; Latham, A.; Benayed, R.; Soslow, R.; Ladanyi, M.; Yaeger, R.; Zehir, A.; more...
    Modern Pathology (2020)

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  • False retained mismatch repair protein expression in microsatellite instability-high cancers is associated with missense mutations in mismatch repair genes
    Meeting Abstract

    Rana, S.; Stadler, Z.; Schwark, A.; Yaeger, R.; Middha, S.; Shia, J.; Zehir, A.; Hechtman, J.
    Journal of Molecular Diagnostics (2019)

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  • Genetic diversity of tumors with mismatch repair deficiency influences anti-PD-1 immunotherapy response
    Journal Article

    Mandal, R.; Samstein, R. M.; Lee, K. W.; Havel, J. J.; Wang, H.; Krishna, C.; Sabio, E. Y.; Makarov, V.; Kuo, F.; Blecua, P.; more...
    Science (2019)

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  • Majority of B2M-mutant and -deficient colorectal carcinomas achieve clinical benefit from immune checkpoint inhibitor therapy and are microsatellite instability-high
    Journal Article

    Middha, S.; Yaeger, R.; Shia, J.; Stadler, Z. K.; King, S.; Guercio, S.; Paroder, V.; Bates, D. D. B.; Rana, S.; Diaz, L. A. Jr; more...
    JCO Precision Oncology (2019)

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  • Colorectal carcinomas containing hypermethylated MLH1 promoter and wild-type BRAF/KRAS are enriched for targetable kinase fusions
    Journal Article

    Cocco, E.; Benhamida, J.; Middha, S.; Zehir, A.; Mullaney, K.; Shia, J.; Yaeger, R.; Zhang, L.; Wong, D.; Villafania, L.; more...
    Cancer Research (2019)

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  • Microsatellite instability is associated with the presence of Lynch syndrome pan-cancer
    Journal Article

    Latham, A.; Srinivasan, P.; Kemel, Y.; Shia, J.; Bandlamudi, C.; Mandelker, D.; Middha, S.; Hechtman, J.; Zehir, A.; Dubard-Gault, M.; more...
    Journal of Clinical Oncology (2019)

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  • Somatic HNF1A mutations in the malignant transformation of hepatocellular adenomas: A retrospective analysis of data from MSK-IMPACT and TCGA
    Journal Article

    Hechtman, J. F.; Abou-Alfa, G. K.; Stadler, Z. K.; Mandelker, D. L.; Roehrl, M. H. A.; Zehir, A.; Vakiani, E.; Middha, S.; Klimstra, D. S.; Shia, J.
    Human Pathology (2019)

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  • Detecting MSI in plasma: Implications for early detection of lynch associated tumors
    Meeting Abstract

    Srinivasan, P.; Tran, C.; Reichel, J.; Patel, J. A.; Hasan, M.; Meng, F.; Jing, X.; Middha, S.; Zehir, A.; Yaeger, R. D.; more...
    Cancer Research (2018)

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  • Pan-cancer microsatellite instability to predict for presence of Lynch syndrome
    Meeting Abstract

    Latham Schwark, A.; Srinivasan, P.; Kemel, Y.; Shia, J.; Bandlamudi, C.; Mandelker, D.; Dubard-Gault, M.; Tran, C.; Middha, S.; Hechtman, J. F.; more...
    Journal of Clinical Oncology (2018)

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  • YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics
    Journal Article

    Fan, P. D.; Narzisi, G.; Jayaprakash, A. D.; Venturini, E.; Robine, N.; Smibert, P.; Germer, S.; Yu, H. A.; Jordan, E. J.; Paik, P. K.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2018)

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