Synapse - Sumit Middha

Results (83)

A deep multiple instance learning framework improves microsatellite instability detection from tumor next generation sequencing

Journal Article

Ziegler, J.; Hechtman, J. F.; Rana, S.; Ptashkin, R. N.; Jayakumaran, G.; Middha, S.; Chavan, S. S.; Vanderbilt, C.; DeLair, D.; Casanova, J.; more...
Nature Communications (2025)

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Defining novel DNA virus-tumor associations and genomic correlates using prospective clinical tumor/normal matched sequencing data

Journal Article

Vanderbilt, C. M.; Bowman, A. S.; Middha, S.; Petrova-Drus, K.; Tang, Y. W.; Chen, X.; Wang, Y.; Chang, J.; Rekhtman, N.; Busam, K. J.; more...
Journal of Molecular Diagnostics (2022)

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Clinical experience of cerebrospinal fluid-based liquid biopsy demonstrates superiority of cell-free DNA over cell pellet genomic DNA for molecular profiling

Journal Article

Bale, T. A.; Yang, S. R.; Solomon, J. P.; Nafa, K.; Middha, S.; Casanova, J.; Sadowska, J.; Skakodub, A.; Ahmad, H.; Yu, H. A.; more...
Journal of Molecular Diagnostics (2021)

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A pan-cancer study of somatic TERT promoter mutations and amplification in 30,773 tumors profiled by clinical genomic sequencing

Journal Article

Gupta, S.; Vanderbilt, C. M.; Lin, Y. T.; Benhamida, J. K.; Jungbluth, A. A.; Rana, S.; Momeni-Boroujeni, A.; Chang, J. C.; Mcfarlane, T.; Salazar, P.; more...
Journal of Molecular Diagnostics (2021)

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Retained mismatch repair protein expression occurs in approximately 6% of microsatellite instability-high cancers and is associated with missense mutations in mismatch repair genes

Journal Article

Hechtman, J. F.; Rana, S.; Middha, S.; Stadler, Z. K.; Latham, A.; Benayed, R.; Soslow, R.; Ladanyi, M.; Yaeger, R.; Zehir, A.; more...
Modern Pathology (2020)

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Comparison of MSK-IMPACT results generated on 2 sequencing platforms: HiSeq2500 and NovaSeq6000

Meeting Abstract

Bacares, R.; Casanova, J.; Lin, Y.; Jayakumaran, G.; Middha, S.; Haque, M.; Syed, M.; Syed, A.; Hu, Y.; Nafa, K.; more...
Journal of Molecular Diagnostics (2019)

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False retained mismatch repair protein expression in microsatellite instability-high cancers is associated with missense mutations in mismatch repair genes

Meeting Abstract

Rana, S.; Stadler, Z.; Schwark, A.; Yaeger, R.; Middha, S.; Shia, J.; Zehir, A.; Hechtman, J.
Journal of Molecular Diagnostics (2019)

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Clinical genomic sequencing of pediatric and adult osteosarcoma reveals distinct molecular subsets with potentially targetable alterations

Journal Article

Suehara, Y.; Alex, D.; Bowman, A.; Middha, S.; Zehir, A.; Chakravarty, D.; Wang, L.; Jour, G.; Nafa, K.; Hayashi, T.; more...
Clinical Cancer Research (2019)

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Dissecting the role of zygosity and lineage in Lynch syndrome-associated microsatellite instability

Meeting Abstract

Srinivasan, P.; Bandlamudi, C.; Shia, J.; Latham, A. S.; Jonsson, P.; Penson, A.; Middha, S.; Hechtman, J.; Zehir, A.; Richards, A.; more...
Cancer Research (2019)

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Identification of prognostic molecular biomarkers in 157 HPV-positive and HPV-negative squamous cell carcinomas of the oropharynx

Journal Article

Dogan, S.; Xu, B.; Middha, S.; Vanderbilt, C. M.; Bowman, A. S.; Migliacci, J.; Morris, L. G. T.; Seshan, V. E.; Ganly, I.
International Journal of Cancer (2019)

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