Synapse - Sumit Middha

Results (18)

Retained mismatch repair protein expression occurs in approximately 6% of microsatellite instability-high cancers and is associated with missense mutations in mismatch repair genes

Journal Article

Hechtman, J. F.; Rana, S.; Middha, S.; Stadler, Z. K.; Latham, A.; Benayed, R.; Soslow, R.; Ladanyi, M.; Yaeger, R.; Zehir, A.; more...
Modern Pathology (2020)

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False retained mismatch repair protein expression in microsatellite instability-high cancers is associated with missense mutations in mismatch repair genes

Meeting Abstract

Rana, S.; Stadler, Z.; Schwark, A.; Yaeger, R.; Middha, S.; Shia, J.; Zehir, A.; Hechtman, J.
Journal of Molecular Diagnostics (2019)

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Dissecting the role of zygosity and lineage in Lynch syndrome-associated microsatellite instability

Meeting Abstract

Srinivasan, P.; Bandlamudi, C.; Shia, J.; Latham, A. S.; Jonsson, P.; Penson, A.; Middha, S.; Hechtman, J.; Zehir, A.; Richards, A.; more...
Cancer Research (2019)

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Majority of B2M-mutant and -deficient colorectal carcinomas achieve clinical benefit from immune checkpoint inhibitor therapy and are microsatellite instability-high

Journal Article

Middha, S.; Yaeger, R.; Shia, J.; Stadler, Z. K.; King, S.; Guercio, S.; Paroder, V.; Bates, D. D. B.; Rana, S.; Diaz, L. A. Jr; more...
JCO Precision Oncology (2019)

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Analysis of the prevalence of microsatellite instability in prostate cancer and response to immune checkpoint blockade

Journal Article

Abida, W.; Cheng, M. L.; Armenia, J.; Middha, S.; Autio, K. A.; Vargas, H. A.; Rathkopf, D.; Morris, M. J.; Danila, D. C.; Slovin, S. F.; more...
JAMA Oncology (2019)

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Colorectal carcinomas containing hypermethylated MLH1 promoter and wild-type BRAF/KRAS are enriched for targetable kinase fusions

Journal Article

Cocco, E.; Benhamida, J.; Middha, S.; Zehir, A.; Mullaney, K.; Shia, J.; Yaeger, R.; Zhang, L.; Wong, D.; Villafania, L.; more...
Cancer Research (2019)

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Microsatellite instability is associated with the presence of Lynch syndrome pan-cancer

Journal Article

Latham, A.; Srinivasan, P.; Kemel, Y.; Shia, J.; Bandlamudi, C.; Mandelker, D.; Middha, S.; Hechtman, J.; Zehir, A.; Dubard-Gault, M.; more...
Journal of Clinical Oncology (2019)

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Somatic HNF1A mutations in the malignant transformation of hepatocellular adenomas: A retrospective analysis of data from MSK-IMPACT and TCGA

Journal Article

Hechtman, J. F.; Abou-Alfa, G. K.; Stadler, Z. K.; Mandelker, D. L.; Roehrl, M. H. A.; Zehir, A.; Vakiani, E.; Middha, S.; Klimstra, D. S.; Shia, J.
Human Pathology (2019)

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Detecting MSI in plasma: Implications for early detection of lynch associated tumors

Meeting Abstract

Srinivasan, P.; Tran, C.; Reichel, J.; Patel, J. A.; Hasan, M.; Meng, F.; Jing, X.; Middha, S.; Zehir, A.; Yaeger, R. D.; more...
Cancer Research (2018)

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Pan-cancer microsatellite instability to predict for presence of Lynch syndrome

Meeting Abstract

Latham Schwark, A.; Srinivasan, P.; Kemel, Y.; Shia, J.; Bandlamudi, C.; Mandelker, D.; Dubard-Gault, M.; Tran, C.; Middha, S.; Hechtman, J. F.; more...
Journal of Clinical Oncology (2018)

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