Synapse - Jin Xu

Results (61)

Synthesis and pharmacology of a morphinan-derived dual Mu−Kappa opioid receptor agonist analgesic

Journal Article

Varga, B. R.; Uprety, R.; Paul, B.; Knoll, A.; Ramos-Gonzalez, N.; Appourchaux, K.; Taylor, T.; Turgutalp, B.; Shinouchi, R.; Eans, S. O.; more...
ACS Chemical Neuroscience (2025)

Fulltext@MSK | Save

Dysregulated expression of the alternatively spliced variant mRNAs of the mu opioid receptor gene, OPRM1, in the medial prefrontal cortex of male human heroin abusers and heroin self-administering male rats

Journal Article

Brown, T. G.; Xu, J.; Hurd, Y. L.; Pan, Y. X.
Journal of Neuroscience Research (2022)

Fulltext@MSK | Save

Oxidative metabolism as a modulator of kratom's biological actions

Journal Article

Chakraborty, S.; Uprety, R.; Slocum, S. T.; Irie, T.; Le Rouzic, V.; Li, X.; Wilson, L. L.; Scouller, B.; Alder, A. F.; Kruegel, A. C.; more...
Journal of Medicinal Chemistry (2021)

Fulltext@MSK | Save

Mu opioids induce biased signaling at the full-length seven transmembrane C-terminal splice variants of the mu opioid receptor gene, Oprm1

Journal Article

Narayan, A.; Hunkele, A.; Xu, J.; Bassoni, D. L.; Pasternak, G. W.; Pan, Y. X.
Cellular and Molecular Neurobiology (2021)

Fulltext@MSK | Save

Enhanced expression of the full-length seven transmembrane mu opioid receptor by MOR-1G, a truncated six transmembrane splice variants through heterodimerization

Meeting Abstract

Zhang, T.; Xu, J.; Pan, Y. X.
FASEB Journal (2020)

Fulltext@MSK | Save

A truncated six transmembrane splice variant MOR-1G enhances expression of the full-length seven transmembrane μ-opioid receptor through heterodimerization

Journal Article

Zhang, T.; Xu, J.; Pan, Y. X.
Molecular Pharmacology (2020)

Fulltext@MSK | Save

Morphine modulates the expression of mu-opioid receptor exon 5-associated full-length C-terminal splice variants by upregulating miR-378a-3p

Journal Article

Lu, Z.; Xu, J.; Wang, Q.; Pan, Y. X.
FASEB Journal (2020)

Fulltext@MSK | Save

Differential regulation of Cav2.2 channel exon 37 variants by alternatively spliced μ-opioid receptors

Journal Article

Gandini, M. A.; Souza, I. A.; Raval, D.; Xu, J.; Pan, Y. X.; Zamponi, G. W.
Molecular Brain (2019)

Fulltext@MSK | Save

Identification of abundant and evolutionarily conserved opioid receptor circular RNAs in the nervous system modulated by morphine

Journal Article

Irie, T.; Shum, R.; Deni, I.; Hunkele, A.; Le Rouzic, V.; Xu, J.; Wilson, R.; Fischer, G. W.; Pasternak, G. W.; Pan, Y. X.
Molecular Pharmacology (2019)

Fulltext@MSK | Save

Pharmacological characterization of levorphanol, a G-protein biased opioid analgesic

Journal Article

Le Rouzic, V.; Narayan, A.; Hunkle, A.; Marrone, G. F.; Lu, Z.; Majumdar, S.; Xu, J.; Pan, Y. X.; Pasternak, G. W.
Anesthesia and Analgesia (2019)

Fulltext@MSK | Save