Synapse - Cristina C Clement

Cristina C Clement

Research Focus

Former Employee. Chemical Biology Program; Research Fellow

Recent additions – View all

Heat shock protein 70 inhibitors. 2. 2,5′-thiodipyrimidines, 5-(phenylthio)pyrimidines, 2-(pyridin-3-ylthio)pyrimidines, and 3-(phenylthio)pyridines as reversible binders to an allosteric site on heat shock protein 70
Journal Article

Taldone, T.; Kang, Y.; Patel, H. J.; Patel, M. R.; Patel, P. D.; Rodina, A.; Patel, Y.; Gozman, A.; Maharaj, R.; Clement, C. C.; more...
Journal of Medicinal Chemistry (2014)

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Heat shock protein 70 inhibitors. 1. 2,5′-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70
Journal Article

Kang, Y.; Taldone, T.; Patel, H. J.; Patel, P. D.; Rodina, A.; Gozman, A.; Maharaj, R.; Clement, C. C.; Patel, M. R.; Brodsky, J. L.; more...
Journal of Medicinal Chemistry (2014)

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YK5 is a novel dual Hsc/Hsp70 inhibitor that is selective for tumor Hsp70 and is a valuable lead for the development of molecules with therapeutic potential in breast cancer
Meeting Abstract

Taldone, Tony; Kang, Yanlong; Rodina, Anna; Maharaj, Ronnie; Gozman, Alexander; Cerchietti, Leandro; Wong, Michael J. H.; Baaklini, Imad; Caldas Lopes, Eloisi; Patel, Hardik J.; more...
Abstracts of Papers of the American Chemical Society (2011)

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Co-authors at MSK

12

Chiosis
8

Kang
8

Rodina ...
6

Aguirre
5

Gozman
5

Taldone
4

Maharaj
4

Moulick
3

Kim
3

Patel
2

Ahn
2

Caldas ...
2

Patel
1

Cerchietti
1

Chiang
1

De Stan...
1

Erdjume...
1

Guo
1

Jiang
1

Kokoszka
1

Massague
1

Ma
1

Melnick
1

Patel
1

She
1

Sun
1

Vilenchik
1

White
1

Wu
1

Zatorska

Types of Work

Publications

Bioorganic & Medicinal Chemistry Letters (2)
Journal of Medicinal Chemistry (2)
Abstracts of Papers of the American Chemical Society (1)
Assay and Drug Development Technologies (1)
Cancer Cell (1)
Cancer Research (1)
FASEB Journal (1)
FEBS Letters (1)
Nature Chemical Biology (1)
Proceedings of the National Academy of Sciences of the United States of America (1)