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Amit U Sinha

Formats
  1. Journal Article (8)
  2. Meeting Abstract (5)
Groups
  1. Sloan Kettering Institute Postdocs (3)
  2. Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center (1)
  3. Center for Hematologic Malignancies (1)
  4. GSK Faculty (1)
  5. Hematologic Malignancies Research (1)
  6. MSK Grad Students (1)

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People
  1. Scott Armstrong (13)
  2. Aniruddha Deshpande (8)
  3. Chun-Wei Chen (7)
  4. Richard Koche (7)
  5. Andrei Krivtsov (5)
  6. Jenny Chang (5)

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Years
  1. 2016 (4)
  2. 2015 (1)
  3. 2014 (3)
  4. 2013 (5)
Publications
  1. Blood (4)
  2. Leukemia (2)
  3. Cancer Cell (1)
  4. Cancer Discovery (1)
  5. Experimental Hematology (1)
  6. Journal of Clinical Investigation (1)

More Publications

Publishers
  1. American Society of Hematology (4)
  2. Nature Publishing Group (4)
  3. American Association for Cancer Research (1)
  4. American Society for Clinical Investigation (1)
  5. Cell Press (1)
  6. Elsevier Science, Inc. (1)

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Results (13)

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  • NUP98 fusion proteins interact with the NSL and MLL1 complexes to drive leukemogenesis
    Journal Article

    Xu, H.; Valerio, D. G.; Eisold, M. E.; Sinha, A.; Koche, R. P.; Hu, W.; Chen, C. W.; Chu, S. H.; Brien, G. L.; Park, C. Y.; more...
    Cancer Cell (2016)

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  • Synergistic inhibition of chromatin modifiers reverses a leukemogenic gene expression program in NPM1 mutant leukemia
    Meeting Abstract

    Kühn, M. W. M.; Song, E.; Feng, Z.; Sinha, A.; Chen, C. W.; Deshpande, A. J.; Cusan, M.; Farnoud, N. R.; Koche, R. P.; Bradner, J. E.; more...
    Oncology Research and Treatment (2016)

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  • Targeting chromatin regulators inhibits leukemogenic gene expression in NPM1 mutant leukemia
    Journal Article

    Kühn, M. W. M.; Song, E.; Feng, Z.; Sinha, A.; Chen, C. W.; Deshpande, A. J.; Cusan, M.; Farnoud, N.; Mupo, A.; Grove, C.; more...
    Cancer Discovery (2016)

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  • MLL-AF9-and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C
    Journal Article

    Zhu, N.; Chen, M.; Eng, R.; DeJong, J.; Sinha, A. U.; Rahnamay, N. F.; Koche, R.; Al-Shahrour, F.; Minehart, J. C.; Chen, C. W.; more...
    Journal of Clinical Investigation (2016)

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  • DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia
    Journal Article

    Chen, C. W.; Koche, R. P.; Sinha, A. U.; Deshpande, A. J.; Zhu, N.; Eng, R.; Doench, J. G.; Xu, H. M.; Chu, S. H.; Qi, J.; more...
    Nature Medicine (2015)

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  • Regulation of HOX gene expression by Af10-mediated conversion of H3k79me1 to H3k79me2
    Meeting Abstract

    Deshpande, A.; Deshpande, A.; Sinha, A.; Chen, L. Y.; Chang, J.; Chen, D.; Koche, R.; Krivtsov, A.; Luo, M.; Bradner, J.; more...
    Experimental Hematology (2014)

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  • KRasG12D-evoked leukemogenesis does not require β-catenin
    Journal Article

    Ng, C. E. L.; Sinha, A.; Krivtsov, A.; Dias, S.; Chang, J.; Armstrong, S. A.; Kalaitzidis, D.
    Leukemia (2014)

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  • Mutations in epigenetic regulators including SETD2 are gained during relapse in paediatric acute lymphoblastic leukaemia
    Journal Article

    Mar, B. G.; Bullinger, L. B.; McLean, K. M.; Grauman, P. V.; Harris, M. H.; Stevenson, K.; Neuberg, D. S.; Sinha, A. U.; Sallan, S. E.; Silverman, L. B.; more...
    Nature Communications (2014)

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  • Myeloid leukemia cells with MLL partial tandem duplication are sensitive to pharmacological inhibition of the H3K79 methyltransferase DOT1L
    Meeting Abstract

    Kühn, M. W. M.; Hadler, M.; Daigle, S. R.; Chen, C. W.; Sinha, A. U.; Krivtsov, A. V.; Olhava, E. J.; Caligiuri, M. A.; Bradner, J. E.; Pollock, R. M.; more...
    Blood (2013)

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  • Regulation of normal and malignant Hoxa gene expression through higher H3K79 methylated states
    Meeting Abstract

    Deshpande, A. J.; Chen, L.; Sinha, A. U.; Zhu, N.; Chen, D.; Chang, J.; Krivtsov, A. V.; Bernt, K.; Bradner, J. E.; Armstrong, S. A.
    Blood (2013)

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