Synapse - Gynecologic Medicine Service

Results (2180)

The frequency of second primary malignancies and colonic polyps in Lynch syndrome with MSI tumors following immune checkpoint blockade

Meeting Abstract

Harrold, E.; Patel, Z.; Maio, A.; Cercek, A.; Yaeger, R.; Segal, N. H.; Reidy, D. L.; O'Reilly, E. M.; Desai, A. M.; Carlo, M. I.; more...
Journal of Clinical Oncology (2022)

Fulltext@MSK | Save

Mechanisms of acquired resistance to TRK inhibitors

Meeting Abstract

Harada, G.; Choudhury, N. J.; Schram, A. M.; Rosen, E.; Murciano-Goroff, Y. R.; Falcon, C. J.; Wilhelm, C.; Kaplanis, L. A.; Liu, D.; Chang, J. C.; more...
Journal of Clinical Oncology (2022)

Fulltext@MSK | Save

Basket study of oral progesterone antagonist onapristone extended release (ONA-XR) in progesterone receptor positive (PR+) recurrent granulosa cell (GCT), low-grade serous ovarian (LGSOC), or endometrioid endometrial cancer (EEC)

Meeting Abstract

Grisham, R. N.; Li, K.; Zhou, Q.; Iasonos, A.; Girshman, J.; Shah, P.; Jang, D.; Kyi, C.; Cohen, S. M.; O'Cearbhaill, R. E.; more...
Journal of Clinical Oncology (2022)

Fulltext@MSK | Save

Dysfunctional CD8+T cells in the tumor microenvironment are associated with response to nivolumab in mismatch repair deficient (dMMR) or hypermutated ovarian (OVCA) or endometrial cancer (EC)

Meeting Abstract

Friedman, C. F.; Zhou, Q.; Iasonos, A.; Holland, A.; Ramirez, L.; Grisham, R. N.; Guo, R.; Lichtman, S. M.; Kyi, C.; Makker, V.; more...
Journal of Clinical Oncology (2022)

Fulltext@MSK | Save

First-in-human study of PC14586, a small molecule structural corrector of Y220C mutant p53, in patients with advanced solid tumors harboring a TP53 Y220C mutation

Meeting Abstract

Dumbrava, E. E.; Johnson, M. L.; Tolcher, A. W.; Shapiro, G.; Thompson, J. A.; El-Khoueiry, A. B.; Vandross, A. L.; Kummar, S.; Parikh, A. R.; Munster, P. N.; more...
Journal of Clinical Oncology (2022)

Fulltext@MSK | Save

Efficacy and safety of rucaparib maintenance treatment in patients from ARIEL3 with platinum-sensitive, recurrent ovarian carcinoma not associated with homologous recombination deficiency

Meeting Abstract

Coleman, R. L.; Oza, A. M.; Lorusso, D.; Aghajanian, C.; Oaknin, A.; Dean, A.; Colombo, N.; Weberpals, J. I.; Clamp, A. R.; Scambia, G.; more...
Journal of Clinical Oncology (2022)

Fulltext@MSK | Save

The bi-steric mTORC1-selective inhibitor RMC-5552 in tumors with activation of mTOR signaling: Preclinical activity in combination with RAS(ON) inhibitors in RAS-addicted tumors, and initial clinical findings from a single agent phase 1/1b study

Meeting Abstract

Burris, H. A. 3rd; Ulahannan, S. V.; Haura, E. B.; Ou, S. H. I.; Capasso, A.; Munster, P. N.; Kitai, H.; Wang, Z.; Hayes, J.; Tao, L.; more...
Journal of Clinical Oncology (2022)

Fulltext@MSK | Save

Electronic research consents for complex early-phase I-II clinical trials integrated with telemedicine visits compared with in-person encounters

Meeting Abstract

Buckley, M. T.; O'Shea, M.; Lipitz-Snyderman, A.; Kuperman, G.; Shah, S.; Redelman-Sidi, Y.; Lengfellner, J. M.; Terzulli, S. L.; Houston, C.; Sabbatini, P.
Journal of Clinical Oncology (2022)

Fulltext@MSK | Save

COVID-19 in patients with gynecologic cancer: A preliminary report from the COVID-19 and Cancer Consortium (CCC19)

Meeting Abstract

Beeghly-Fadiel, A.; Prescott, L. S.; Ruiz-Garcia, E.; Hwang, C.; Heilman, H.; McKay, R. R.; Saliby, R. M.; Lau, S.; Nagaraj, G.; Puc, M.; more...
Journal of Clinical Oncology (2022)

Fulltext@MSK | Save

ENGOT-ov60/GOG-3052/RAMP 201: A phase 2 study of VS-6766 (RAF/MEK clamp) alone and in combination with defactinib (FAK inhibitor) in recurrent low-grade serous ovarian cancer (LGSOC)

Meeting Abstract

Banerjee, S. N.; Monk, B. J.; Van Nieuwenhuysen, E.; Moore, K. N.; Oaknin, A.; Fabbro, M.; Colombo, N.; O'Malley, D. M.; Coleman, R. L.; Oza, A. M.; more...
Journal of Clinical Oncology (2022)

Fulltext@MSK | Save