Synapse - Gynecologic Medicine Service

Results (2180)

A phase Ib dose-escalation study of binimetinib (MEK162) in combination with weekly paclitaxel in patients with platinum-resistant epithelial ovarian, fallopian tube or primary peritoneal cancer

Meeting Abstract

Grisham, R. N.; Gordon, M. S.; Harb, W. A.; Aghajanian, C.; McMeekin, D. S.; McKinley, K.; Anderson, L. R.; Chavira, R.; Christy-Bittel, J.; Barrett, E.; more...
Journal of Clinical Oncology (2015)

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A randomized phase III study of trabectedin (T) or dacarbazine (D) for the treatment of patients (pts) with advanced liposarcoma (LPS) or leiomyosarcoma (LMS)

Meeting Abstract

Demetri, G. D.; von Mehren, M.; Jones, R. L.; Hensley, M. L.; Schuetze, S.; Staddon, A. P.; Milhem, M. M.; Elias, A. D.; Ganjoo, K. N.; Tawbi, H. A. H.; more...
Journal of Clinical Oncology (2015)

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A phase I study of continuous veliparib in combination with IV carboplatin/paclitaxel or IV/IP paclitaxel/cisplatin and bevacizumab in newly diagnosed patients with previously untreated epithelial ovarian, fallopian tube, or primary peritoneal cancer: An NRG Oncology/Gynecologic Oncology Group study

Meeting Abstract

Bell-Mcguinn, K. M.; Brady, W. E.; Schilder, R. J.; Fracasso, P. M.; Moore, K. N.; Walker, J. L.; Duska, L. R.; Mathews, C. A.; Chen, A.; Shepherd, S. P.; more...
Journal of Clinical Oncology (2015)

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Randomized phase III trial of carboplatin/paclitaxel alone (CP) or in combination with bevacizumab followed by bevacizumab (CPB) and secondary cytoreduction surgery in platinum-sensitive recurrent ovarian cancer: GOG0213, an NRG Oncology/GOG Study-Analysis of patient reported outcomes (PRO) on chemotherapy randomization

Meeting Abstract

Basen-Engquist, K.; Huang, H. Q.; Herzog, T. J.; Armstrong, D. K.; Sabbatini, P.; Walker, J. L.; Kim, B. G.; Fujiwara, K.; Tewari, K. S.; O'Malley, D. M.; more...
Journal of Clinical Oncology (2015)

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A randomized phase II study of paclitaxel/carboplatin/bevacizumab, paclitaxel/carboplatin/temsirolimus and ixabepilone/carboplatin/bevacizumab as initial therapy for measurable stage III or IVA, stage IVB or recurrent endometrial cancer, GOG-86P

Meeting Abstract

Aghajanian, C.; Filiaci, V. L.; Dizon, D. S.; Carlson, J.; Powell, M. A.; Secord, A. A.; Tewari, K. S.; Bender, D.; O'Malley, D. M.; Stuckey, A.; more...
Journal of Clinical Oncology (2015)

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Immune checkpoint modulation: Rational design of combination strategies

Journal Article

Zamarin, D.; Postow, M. A.
Pharmacology & Therapeutics (2015)

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A phase I pharmacokinetic and safety analysis of epothilone folate (BMS-753493), a folate receptor targeted chemotherapeutic agent in humans with advanced solid tumors

Journal Article

Peethambaram, P. P.; Hartmann, L. C.; Jonker, D. J.; De Jonge, M.; Plummer, E. R.; Martin, L.; Konner, J.; Marshall, J.; Goss, G. D.; Teslenko, V.; more...
Investigational New Drugs (2015)

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Replication-competent viruses as cancer immunotherapeutics: Emerging clinical data

Journal Article

Zamarin, D.; Pesonen, S.
Human Gene Therapy (2015)

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Approach to therapy of diffuse large B-cell lymphoma in the elderly: The International Society of Geriatric Oncology (SIOG) expert position commentary

Journal Article

Morrison, V. A.; Hamlin, P.; Soubeyran, P.; Stauder, R.; Wadhwa, P.; Aapro, M.; Lichtman, S. M.
Annals of Oncology (2015)

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Comprehensive predictive biomarker evaluation in two phase II clinical trials of the PI3K/mTOR inhibitor GDC-0980 in metastatic renal cell carcinoma and advanced endometrial cancer

Meeting Abstract

Spoerke, J. M.; Makker, V.; Aghajanian, C.; Thomas, P.; Motzer, R. J.; Lauchle, J. O.; Parmar, H.; Gilbert, H.; Lin, W.; O'Keeffe, B.; more...
Molecular Cancer Therapeutics (2015)

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