Synapse - Computational Oncology Service

Results (228)

TP53 state dictates genome stability, clinical presentation and outcomes in myelodysplastic syndromes

Meeting Abstract

Bernard, E.; Nannya, Y.; Yoshizato, T.; Hasserjian, R. P.; Saiki, R.; Shiozawa, Y.; Devlin, S. M.; Tuechler, H.; Sarian, A.; Malcovati, L.; more...
Blood (2019)

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Comprehensive genomic analysis of metastatic non–clear-cell renal cell carcinoma to identify therapeutic targets

Journal Article

Carlo, M. I.; Khan, N.; Zehir, A.; Patil, S.; Ged, Y.; Redzematovic, A.; Coskey, D. T.; Hyman, D. M.; Ladanyi, M.; Chen, Y. B.; more...
JCO Precision Oncology (2019)

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Analysis of tumor genomic pathway alterations using broad-panel next-generation sequencing in surgically resected lung adenocarcinoma

Journal Article

Zhou, J.; Sanchez-Vega, F.; Caso, R.; Tan, K. S.; Brandt, W. S.; Jones, G. D.; Yan, S.; Adusumilli, P. S.; Bott, M.; Huang, J.; more...
Clinical Cancer Research (2019)

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First-line pembrolizumab (P), trastuzumab (T), capecitabine (C) and oxaliplatin (O) in HER2-positive metastatic esophagogastric adenocarcinoma

Meeting Abstract

Janjigian, Y. Y.; Maron, S.; Chou, J. F.; Gabler, A. R.; Simmons, M. Z.; Momtaz, P.; Shcherba, M.; Ku, G. Y.; Won, E.; Sanchez-Vega, F.; more...
Annals of Oncology (2019)

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A rectal cancer organoid platform to study individual responses to chemoradiation

Journal Article

Ganesh, K.; Wu, C.; O’Rourke, K. P.; Szeglin, B. C.; Zheng, Y.; Sauvé, C. E. G.; Adileh, M.; Wasserman, I.; Marco, M. R.; Kim, A. S.; more...
Nature Medicine (2019)

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First-line pembrolizumab (P), trastuzumab (T), capecitabine (C) and oxaliplatin (O) in HER2-positive metastatic esophagogastric adenocarcinoma

Meeting Abstract

Janjigian, Y. Y.; Maron, S. B.; Chou, J. F.; Gabler, A.; Simmons, M.; Momtaz, P.; Sanchez-Vega, F.; Shcherba, M.; Ku, G. Y.; Won, E.; more...
Journal of Clinical Oncology (2019)

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Clinical and molecular factors predicting resistance to first-line (1L) FOLFOX in patients (pts) with advanced esophagogastric cancer (EGA) and patterns of subsequent therapy

Meeting Abstract

Greally, M.; Walch, H. S.; Chou, J. F.; Capanu, M.; Kelsen, D. P.; Ilson, D. H.; Janjigian, Y. Y.; Schultz, N.; Ku, G. Y.
Journal of Clinical Oncology (2019)

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First-line pembrolizumab (P), trastuzumab (T), capecitabine (C) and oxaliplatin (O-) in HER2-positive metastatic esophagogastric adenocarcinoma (mEGA)

Meeting Abstract

Janjigian, Y. Y.; Chou, J. F.; Simmons, M.; Momtaz, P.; Sanchez-Vega, F.; Shcherba, M.; Ku, G. Y.; Won, E.; Chong, C. R.; Gerdes, H.; more...
Journal of Clinical Oncology (2019)

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Genomic profiling of metastatic breast cancer identifies the Hippo pathway to be a key determinant of CDK4/6 inhibitor sensitivity

Meeting Abstract

Razavi, P.; Li, Q.; Li, Z.; Brown, D. N.; Ping, C.; Shen, R.; Sanchez-Vega, F.; Schultz, N. D.; Baselga, J.; Scaltriti, M.; more...
Cancer Research (2019)

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Oncologic therapy for solid tumors alters the risk of clonal hematopoiesis

Meeting Abstract

Bolton, K.; Ptashkin, R.; Braunstein, L.; Gao, T.; Devlin, S. M.; Kelly, D.; Coombs, C.; Patel, M.; Moarii, M.; Bernard, E.; more...
Cancer Research (2019)

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