Synapse - GDMT, Medicine

Results (1915)

GOG-3097/ENGOT-ov81/GTG-UK/RAMP 301: A phase 3, randomized trial evaluating avutometinib plus defactinib compared with investigator's choice of treatment in patients with recurrent low grade serous ovarian cancer

Journal Article

Grisham, R.; Monk, B. J.; Van Nieuwenhuysen, E.; Moore, K. N.; Fabbro, M.; O'Malley, D. M.; Oaknin, A.; Thaker, P.; Oza, A. M.; Colombo, N.; more...
International Journal of Gynecological Cancer (2025)

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Health disparities among women who received treatment for 1L advanced and recurrent endometrial cancer in the United States

Meeting Abstract

McClain, K. M.; Prabhu, V. S.; Marupuru, S.; Meng, K.; Tran, V.; Woodhouse, K.; Meng, R.; Green, A. K.; Makker, V.
Cancer Epidemiology Biomarkers and Prevention (2025)

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Embracing and implementing the WHO cervical cancer elimination campaign goals: A consensus statement by SGO, ACOG, ASCCP, ASTRO, and ABS on minimum quality care standards for cervical cancer patients in the U.S

Editorial

Zhou, N. Y.; Beavis, A. L.; Lin, L. L.; Neibart, S. S.; Chino, J.; Pierce, J. Y.; O'Cearbhaill, R. E.; Dewdney, S. B.; Farid, H.; Chen, L. M.; more...
Gynecologic Oncology (2025)

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Primary analysis of EPIK-O/ENGOT-ov61: Alpelisib plus olaparib versus chemotherapy in platinum-resistant or platinum-refractory high-grade serous ovarian cancer without BRCA mutation

Journal Article

Konstantinopoulos, P. A.; Kim, J. W.; Freyer, G.; Lee, J. Y.; Gaba, L.; Grisham, R. N.; Colombo, N.; Wu, X.; Sehouli, J.; Cruz, F.; more...
Journal of Clinical Oncology (2025)

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Immuno-oncologyDupilumab for bullous pemphigoid related to immune checkpoint inhibitors: A retrospective case series

Journal Article

Nykaza, I.; Moy, A.; Dusza, S. W.; Moskowitz, A.; Iyer, G.; Iqbal, A.; Motzer, R.; Ilson, D. H.; O'Cearbhaill, R. E.; Kazi, R.; more...
The Oncologist (2025)

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A first-in-human phase 1 study Of LY4170156, an antibody-drug conjugate targeting folate receptor α (FRα)-expressing advanced solid tumors (trial in progress)

Meeting Abstract

Ray-Coquard, I. L.; O'Malley, D. M.; Oaknin, A.; Pothuri, B.; Lorusso, D.; Eskander, R. N.; Westin, S. N.; Lakhani, N.; McKean, W. B.; Koyama, T.; more...
International Journal of Gynecological Cancer (2025)

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An open-label, multicentre, phase 2 study of trastuzumab deruxtecan in patients with HER2-expressing solid tumours: DESTINY-PanTumor02 Part 2

Meeting Abstract

Oaknin, A.; Lee, J. Y.; Makker, V.; Oh, D. Y.; Anoka, C.; Jung, L.; Puvvada, S.; Simões, J.; Meric-Bernstam, F.
International Journal of Gynecological Cancer (2025)

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Multimodal AI modeling of clinical panel-based sequencing for HRD detection in ovarian cancer

Meeting Abstract

Alsaafin, A.; Pollard, T.; Aukerman, A. T.; Boehm, K.; Pasha, A.; Moore, D.; Rusk, N.; Begum, A.; Sullivan, M. W.; Graves, S.; more...
Clinical Cancer Research (2025)

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Phase I/II clinical investigation of invikafusp alfa, a first-in-class TCR-beta chain-targeted bispecific antibody, as monotherapy in patients with anti-PD(L)1-resistant, antigen-rich gastrointestinal (GI) cancers

Meeting Abstract

Fernandez, E. E.; Garralda, E.; Parikh, A.; Italiano, A.; Hollebecque, A.; Marabelle, A.; Friedman, C.; Sullivan, R.; Tschernia, N.; Juarez, M. M. H.; more...
Annals of Oncology (2025)

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Randomized study evaluating optimal dose, efficacy, and safety of E7386 plus lenvatinib versus treatment of physician's choice in advanced/recurrent endometrial carcinoma previously treated with platinum-based chemotherapy and immune checkpoint inhibitors

Journal Article

Eskander, R. N.; Lee, J. Y.; Mirza, M. R.; Lorusso, D.; MacKay, H.; Ray-Coquard, I.; Oaknin, A.; Gonzalez-Martin, A.; Hasegawa, K.; Corr, B. R.; more...
International Journal of Gynecological Cancer (2025)

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