Synapse - Sarcoma Service (Pediatrics)

Results (44)

Germline pathogenic variants in DNA repair pathways: A key feature in a significant subset of translocation-associated sarcomas

Journal Article

Saoud, C.; Dermawan, J. K.; Arora, K.; Tap, W. D.; Reed, D.; Slotkin, E. K.; Wexler, L. H.; Murciano-Goroff, Y. R.; Latham, A.; Mandelker, D. L.; more...
npj Precision Oncology (2025)

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Undifferentiated pleomorphic sarcoma in children and young adults: A comprehensive clinicopathologic, genomic, and epigenetic comparison with adult counterparts

Journal Article

Saoud, C.; Gundem, G.; Vanderbilt, C. M.; Wexler, L. H.; Reed, D. R.; Tap, W.; Singer, S.; Villafania, L. B.; Papaemmanouil, E.; Benhamida, J.; more...
Modern Pathology (2025)

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Does longitudinal NGS testing provide clinically relevant information in translocation associated sarcomas (TAS)?

Meeting Abstract

Yakoub, M.; Saoud, C.; Tap, W.; Wexler, L.; Hameed, M.; Antonescu, C.
Laboratory Investigation (2025)

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Harmonization of the upfront osteosarcoma treatment paradigm for adolescents and young adults

Journal Article

Daukshus, N. P.; Avutu, V.; Long Sarro, E.; Kinnaman, M. D.; Slotkin, E. K.; Thornton, K.; Dickson, M. A.; Sklarin, N. T.; Tap, W. D.; Glade Bender, J.
Journal of Adolescent and Young Adult Oncology (2025)

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Histology-specific clinical trial of lenvatinib and pembrolizumab in patients with sarcoma

Journal Article

Movva, S.; Seier, K.; Avutu, V.; Banks, L. B.; Chan, J.; Chi, P.; Dickson, M. A.; Gounder, M. M.; Kelly, C. M.; Keohan, M. L.; more...
Clinical Cancer Research (2024)

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Pediatric leukemia roadmaps are a guide for positive metastatic bone sarcoma trials

Journal Article

Reed, D. R.; Tulpule, A.; Metts, J.; Trucco, M.; Robertson-Tessi, M.; O'Donohue, T. J.; Iglesias-Cardenas, F.; Isakoff, M. S.; Mauguen, A.; Shukla, N.; more...
Journal of Clinical Oncology (2024)

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NF1-driven rhabdomyosarcoma phenotypes: A comparative clinical and molecular study of NF1-mutant rhabdomyosarcoma and NF1-associated malignant triton tumor

Journal Article

de Traux de Wardin, H.; Dermawan, J. K.; Vanoli, F.; Jiang, S. C.; Singer, S.; Chi, P.; Tap, W.; Wexler, L. H.; Antonescu, C. R.
JCO Precision Oncology (2024)

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Overcoming clinical resistance to EZH2 inhibition using rational epigenetic combination therapy

Journal Article

Kazansky, Y.; Cameron, D.; Mueller, H. S.; Demarest, P.; Zaffaroni, N.; Arrighetti, N.; Zuco, V.; Kuwahara, Y.; Somwar, R.; Ladanyi, M.; more...
Cancer Discovery (2024)

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Genomic profiling of pleomorphic rhabdomyosarcoma reveals a genomic signature distinct from that of embryonal rhabdomyosarcoma

Journal Article

Saoud, C.; Dermawan, J. K.; Sharma, A. E.; Tap, W.; Wexler, L. H.; Antonescu, C. R.
Genes Chromosomes and Cancer (2024)

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Chromoplexy is a frequent early clonal event in EWSR1-rearranged round cell sarcomas that can be detected using clinically validated targeted sequencing panels

Journal Article

Dermawan, J. K.; Slotkin, E.; Tap, W. D.; Meyers, P.; Wexler, L.; Healey, J.; Vanoli, F.; Vanderbilt, C. M.; Antonescu, C. R.
Cancer Research (2024)

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