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Results (13855)

Correlation of tumour-associated macrophage, but not tumour-infiltrating lymphocyte, levels with progression-free survival in patients with metastatic renal cell carcinoma treated with axitinib

Meeting Abstract

Williams, J. A.; Martini, J. F.; Escudier, B.; Rini, B. I.; Motzer, R. J.; Tarazi, J.; Li, S.; English, P. A.
European Journal of Cancer (2014)

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RNA G-quadruplexes cause elF4A-dependent oncogene translation in cancer

Meeting Abstract

Wendel, H.; Singh, K.; Wolfe, A.; Zhong, Y.; Drewe, P.; Porco, J.; Pelletier, J.; Ratsch, G.
European Journal of Cancer (2014)

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Novel regulation of estrogen receptor transcription by the PI3K pathway

Meeting Abstract

Toska, E.; Elkabets, M.; Bosch, A.; Litvin, O.; Scaltriti, M.; Baselga, J.
European Journal of Cancer (2014)

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Phase I study of the selective BRAFV600 inhibitor encorafenib (LGX818) combined with cetuximab and with or without the α-specific PI3K inhibitor alpelisib (BYL719) in patients with advanced BRAF mutant colorectal cancer

Meeting Abstract

Tabernero, J.; van Geel, R.; Bendell, J. C.; Spreafico, A.; Schuler, M.; Yoshino, T.; Delord, J. P.; Yamada, Y.; Lolkema, M. P.; Fans, J. E.; more...
European Journal of Cancer (2014)

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Interim phase 2 results of study CO-1686-008: A phase 1/2 study of the irreversible, mutant selective, EGFR inhibitor rociletinib (CO-1686) in patients with advanced non small cell lung cancer

Meeting Abstract

Soria, J.; Sequist, L. V.; Goldman, J. W.; Wakelee, H. A.; Gadgeel, S. M.; Varga, A.; Yu, H. A.; Solomon, B. J.; Ou, S. H.; Papadimitrakopoulou, V.; more...
European Journal of Cancer (2014)

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AKT3 activation mediates resistance to HER2-targeted therapies in HER2-amplified breast cancer

Meeting Abstract

Carmona Sanz, F.; Montemurro, F.; Rossi, V.; Verma, C.; Berger, M.; Baselga, J.; Scaltriti, M.
European Journal of Cancer (2014)

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Targeting the cell cycle regulated CDC7 kinase pathway as a novel therapeutic approach for hematologic malignancies

Meeting Abstract

Santos, R.; Shum, D.; Churchill, M.; Mukherjee, S.; Brentjens, R. J.; Jurcic, J. G.; Kelly, T.; Djaballah, H.; Frattini, M. G.
Clinical Lymphoma, Myeloma and Leukemia (2014)

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Inhibition of the cell cycle regulated Cdc7 kinase pathway is an efficacious therapeutic approach for hematologic malignancies and solid tumors

Meeting Abstract

Santos, R.; Shum, D.; Carrillo, D.; Zhang, R.; Churchill, M.; Mukherjee, S.; Brentjens, R.; Radu, C.; Kelly, T. J.; Djaballah, H.; more...
European Journal of Cancer (2014)

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Druggability of p16 deleted pediatric leukemia: The novel cell line POETIC3 identifies potential agents and drug combinations for mechanism based targeted therapeutics

Meeting Abstract

Reimer, J.; Kovulchuk, A.; Ruan, Y.; Shah, R.; Jayanthan, A.; Perinpanayagam, M.; Truong, T.; Auer-Grzesiak, I.; Luider, J.; Kovulchuk, O.; more...
European Journal of Cancer (2014)

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Clinical safety and activity in a phase I trial of AG-120, a first in class, selective, potent inhibitor of the IDH1-mutant protein, in patients with IDH1 mutant positive advanced hematologic malignancies

Meeting Abstract

Pollyea, D. A.; de Botton, S.; Fathi, A. T.; Stein, E. M.; Tallman, M. S.; Agresta, S.; Bowden, C.; Fan, B.; Prah, M.; Yang, H.; more...
European Journal of Cancer (2014)

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