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Results (1376)

Relocation of collapsed forks to the nuclear pore complex depends on sumoylation of DNA repair proteins and permits Rad51 association

Journal Article

Whalen, J. M.; Dhingra, N.; Wei, L.; Zhao, X.; Freudenreich, C. H.
Cell Reports (2020)

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Modeling cancer genomic data in yeast reveals selection against ATM function during tumorigenesis

Journal Article

Hohl, M.; Mojumdar, A.; Hailemariam, S.; Kuryavyi, V.; Ghisays, F.; Sorenson, K.; Chang, M.; Taylor, B. S.; Patel, D. J.; Burgers, P. M.; more...
PLoS Genetics (2020)

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Mycobacterial DNA polymerase I: Activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme

Journal Article

Ghosh, S.; Goldgur, Y.; Shuman, S.
Nucleic Acids Research (2020)

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Substrate analogs that trap the 2′-phospho-ADP-ribosylated RNA intermediate of the Tpt1 (tRNA 2′-phosphotransferase) reaction pathway

Journal Article

Dantuluri, S.; Abdullahu, L.; Munir, A.; Katolik, A.; Damha, M. J.; Shuman, S.
RNA (2020)

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A p53-independent DNA damage response suppresses oncogenic proliferation and genome instability

Journal Article

Fagan-Solis, K. D.; Simpson, D. A.; Kumar, R. J.; Martelotto, L. G.; Mose, L. E.; Rashid, N. U.; Ho, A. Y.; Powell, S. N.; Wen, Y. H.; Parker, J. S.; more...
Cell Reports (2020)

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Single-molecule optical tweezers studies of translation

Book Section

Qu, X.
In Joo, C.; Rueda, D. (Eds.) Biophysics of RNA-Protein Interactions: A Mechanistic View (2019)

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Structure-function analysis of the phosphoesterase component of the nucleic acid end-healing enzyme Runella slithyformis HD-Pnk

Journal Article

Munir, A.; Shuman, S.
Journal of Bacteriology (2019)

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Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection

Journal Article

Jia, N.; Unciuleac, M. C.; Xue, C.; Greene, E. C.; Patel, D. J.; Shuman, S.
Proceedings of the National Academy of Sciences of the United States of America (2019)

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Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: Conformational switches in the kinase upon binding of the GTP phosphate donor

Journal Article

Banerjee, A.; Goldgur, Y.; Schwer, B.; Shuman, S.
Nucleic Acids Research (2019)

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The telomere-binding protein Rif2 and ATP-bound Rad50 have opposing roles in the activation of yeast Tel1(ATM) kinase

Journal Article

Hailemariam, S.; De Bona, P.; Galletto, R.; Hohl, M.; Petrini, J. H.; Burgers, P. M.
Journal of Biological Chemistry (2019)

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