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Overcoming cancer drug resistance

Meeting Abstract

Sawyers, C. L.
Cancer Research (2012)

RAS-independent dimerization of BRAF(V600E) splicing variants promotes resistance to RAF inhibitors

Meeting Abstract

Poulikakos, P. I.; Persaud, Y.; Janakiraman, M.; Kong, X.; Ng, C.; Moriceau, G.; Shi, H.; Atefi, M.; Titz, B.; Gabay, M. T.; more...
Cancer Research (2012)

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RAS signaling pathway gene mutations and acquired resistance to EGFR tyrosine-kinase inhibitors in EGFR mutant lung cancer

Meeting Abstract

Ohashi, K.; Chmielecki, J.; Lin, Y. L.; Pan, H. L.; Vnencak-Jones, C.; Arcila, M.; Wang, L.; Fernandez, L.; Keisuke, A.; Shien, K.; more...
Cancer Research (2012)

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Targeting cancer cell metabolism in pancreatic cancer: p53, a key regulator of glycolysis and a major factor deciding the outcome of targeting the Warburg effect

Meeting Abstract

Rajeshkumar, N. V.; Dutta, P.; Kamphorst, J.; Le, A.; Yabuuchi, S.; de Wilde, R. F.; Campbell, N. R.; De Oliveira, E.; De Jesus-Acosta, A.; Rabinowitz, J.; more...
Cancer Research (2012)

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mTOR kinase inhibition relieves feedback suppression of receptor tyrosine kinase leading to a biphasic regulation of AKT signaling in breast cancer cells

Meeting Abstract

Rodrik-Outmezguine, V. S.; Chandarlapaty, S.; Pagano, N. C.; Poulikakos, P. I.; Scaltriti, M.; Baselga, J.; Guichard, S.; Rosen, N.
Cancer Research (2012)

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Metastatic and non-metastatic isogenic breast cancer cells lines show different metabolic signatures in response to intermittent hypoxia and transient glutamine/glucose deprivation

Meeting Abstract

Simoes, R. V.; Ackerstaff, E.; Serganova, I.; Kruchevsky, N.; Sukenick, G.; Blasberg, R.; Koutcher, J. A.
Cancer Research (2012)

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Genomic and functional analysis of Myxofibrosarcoma identifies novel prognostic markers and promising therapeutic targets

Meeting Abstract

Lee, A. Y.; Crago, A. M.; Agaram, N. P.; Okada, T.; DeCarolis, P.; O'Connor, R. B.; Qin, L. X.; Khanin, R.; Antipin, Y.; Reva, B. A.; more...
Cancer Research (2012)

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Understanding the role of stem-like tumor cells in mouse models of high-grade gliomas

Meeting Abstract

Barrett, L. E.; Benezra, R.
Cancer Research (2012)

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Prostate-specific inhibition of PI3 Kinase and protein synthesis as a therapy for advanced hormone cancer

Meeting Abstract

Baiz, D.; Choi, Y. A.; Karpova, Y.; Yancey, D.; Hassan, S.; Sadelain, M.; Debinsk, W.; Kulik, G.
Cancer Research (2012)

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HSP90 inhibitors target KRAS mutant human tumors through degradation of STK33

Meeting Abstract

Azoitei, N.; Hoffmann, C. M.; Ellegast, J. M.; Ball, C. R.; Obermayer, K.; Gossele, U.; Koch, B.; Faber, K.; Genze, F.; Schrader, M.; more...
Cancer Research (2012)

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