Identifying cluster subtypes for intentions to have colorectal cancer screening among non-compliant intermediate-risk siblings of individuals with colorectal cancer Journal Article


Authors: Manne, S. L.; Coups, E. J.; Winkel, G.; Markowitz, A.; Meropol, N. J.; Lesko, S. M.; Jacobsen, P. B.; Haller, D.; Jandorf, L.; Peterson, S. K.
Article Title: Identifying cluster subtypes for intentions to have colorectal cancer screening among non-compliant intermediate-risk siblings of individuals with colorectal cancer
Abstract: Although first-degree relatives of colorectal cancer (CRC) patients diagnosed at an early age are at increased risk for CRC, their compliance with colorectal cancer screening (CRCS) is not high. Relatively little is known about why these intermediate-risk family members do not comply with CRCS. Study aims were to identify subgroups of siblings of individuals diagnosed with CRC prior to age 61 who were not compliant with CRCS using cluster analysis and to identify demographical, medical and attitudinal correlates of cluster membership. A total of 421 siblings completed measures of pros, cons, processes of change, CRCS knowledge, physician and family CRCS support, CRC risk, severity, preventability, curability, closeness with the affected sibling, distress about the sibling's cancer and screening intentions. Three clusters characterized as 'Positive about Screening', 'Uncertain about Screening' and 'Negative about Screening' were identified. External validation revealed that those in the Positive about Screening cluster reported significantly stronger CRCS intentions than those who are Uncertain about Screening and Negative about Screening clusters. Results provide an empirical typology for understanding motivations for CRCS among at-risk family members and may lead to the development of more effective interventions to improve screening uptake.
Keywords: cancer risk; colorectal cancer; genetic predisposition to disease; cluster analysis; cancer screening; mass screening; siblings; colorectal neoplasms; predictor variable; attitude to illness; sibling; health knowledge, attitudes, practice; patient acceptance of health care
Journal Title: Health Education Research
Volume: 24
Issue: 5
ISSN: 0268-1153
Publisher: Oxford University Press  
Date Published: 2009-10-01
Start Page: 897
End Page: 908
Language: English
DOI: 10.1093/her/cyp043
PUBMED: 19654222
PROVIDER: scopus
PMCID: PMC2738960
DOI/URL:
Notes: --- - "Export Date: 30 November 2010" - "CODEN: HERPE" - "Source: Scopus"
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  1. Arnold J Markowitz
    138 Markowitz