Non-small cell lung cancer, version 6.2015 Journal Article


Authors: Ettinger, D. S.; Wood, D. E.; Akerley, W.; Bazhenova, L. A.; Borghaei, H.; Camidge, D. R.; Cheney, R. T.; Chirieac, L. R.; D'Amico, T. A.; Demmy, T. L.; Dilling, T. J.; Dobelbower, M. C.; Govindan, R.; Grannis, F. W., Jr.; Horn, L.; Jahan, T. M.; Komaki, R.; Krug, L. M.; Lackner, R. P.; Lanuti, M.; Lilenbaum, R.; Lin, J.; Loo, B. W., Jr.; Martins, R.; Otterson, G. A.; Patel, J. D.; Pisters, K. M.; Reckamp, K.; Riely, G. J.; Rohren, E.; Schild, S. E.; Shapiro, T. A.; Swanson, S. J.; Tauer, K.; Yang, S. C.; Gregory, K.; Hughes, M.
Article Title: Non-small cell lung cancer, version 6.2015
Abstract: These NCCN Guidelines Insights focus on recent updates to the 2015 NCCN Guidelines for Non-Small Cell Lung Cancer (NSCLC). Appropriate targeted therapy is very effective in patients with advanced NSCLC who have specific genetic alterations. Therefore, it is important to test tumor tissue from patients with advanced NSCLC to determine whether they have genetic alterations that make them candidates for specific targeted therapies. These NCCN Guidelines Insights describe the different testing methods currently available for determining whether patients have genetic alterations in the 2 most commonly actionable genetic alterations, notably anaplastic lymphoma kinase (ALK) gene rearrangements and sensitizing epidermal growth factor receptor (EGFR) mutations. Copyright © 2015 by the National Comprehensive Cancer Network.
Keywords: genetics; carcinoma, non-small-cell lung; lung neoplasms; practice guideline; genetic screening; genetic testing; humans; human
Journal Title: Journal of the National Comprehensive Cancer Network
Volume: 13
Issue: 5
ISSN: 1540-1405
Publisher: Harborside Press  
Date Published: 2015-05-01
Start Page: 515
End Page: 524
Language: English
PUBMED: 25964637
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 3 October 2016 -- Source: Scopus
Citation Impact
MSK Authors
  1. Lee M Krug
    178 Krug
  2. Gregory J Riely
    599 Riely
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