Neuro-ophthalmologic manifestations of a paraneoplastic syndrome and testicular carcinoma Journal Article


Authors: Bennett, J. L.; Galetta, S. L.; Frohman, L. P.; Mourelatos, Z.; Gultekin, S. H.; Dalmau, J. O.; Posner, J. B.
Article Title: Neuro-ophthalmologic manifestations of a paraneoplastic syndrome and testicular carcinoma
Abstract: The authors report two patients with testicular cancer who exhibited supranuclear gaze disorders as a manifestation of a paraneoplastic brainstem encephalomyelitis. In the first patient, neuro-ophthalmic dysfunction was accompanied by a prominent limbic encephalitis whereas in the second patient, an unusual, mixed pendular and jerk nystagmus was manifested. Neuroimaging revealed an enhancing hypothalamic mass in the first patient and was negative in the second. Blood from both patients contained an antibody previously reported in a patient with limbic encephalitis and testicular cancer.
Keywords: encephalitis; cerebellar degeneration
Journal Title: Neurology
Volume: 52
Issue: 4
ISSN: 0028-3878
Publisher: Lippincott Williams & Wilkins  
Date Published: 1999-03-10
Start Page: 864
End Page: 867
Language: English
ACCESSION: WOS:000079126400038
PROVIDER: wos
PUBMED: 10078744
DOI: 10.​1212/​WNL.​52.​4.​864
Notes: Article -- Source: Wos
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  1. Jerome B Posner
    211 Posner
  2. Josep O Dalmau
    101 Dalmau