A broadly applicable method for the efficient synthesis of alpha-O-linked glycopeptides and clustered sialic acid residues Journal Article

  

Authors:	Schwarz, J. B.; Kuduk, S. D.; Chen, X. T.; Sames, D.; Glunz, P. W.; Danishefsky, S. J.
Article Title:	A broadly applicable method for the efficient synthesis of alpha-O-linked glycopeptides and clustered sialic acid residues
Abstract:	The total syntheses of complex sialylated cell-surface antigens have been accomplished. The target systems include 2.3-STF, STn, 2,6-STF, and glycophorin antigens. In addition,an alpha-O-linked serine glycoside of an entire Lewis blood group (Y) antigen has been assembled.
Keywords:	antigen; building-blocks; solid-phase synthesis; oligosaccharides; sialylation; donors; muc-1 mucin; tn; cancer; promoted reactions; glycosyl
Journal Title:	Journal of the American Chemical Society
Volume:	121
Issue:	12
ISSN:	0002-7863
Publisher:	American Chemical Society
Date Published:	1999-03-31
Start Page:	2662
End Page:	2673
Language:	English
ACCESSION:	WOS:000079510100003
DOI:	10.1021/ja9833265
PROVIDER:	wos
Notes:	Article -- Source: Wos

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