Kinetic concepts in the systemic drug therapy of breast cancer Journal Article
| Author: | Norton, L. |
| Article Title: | Kinetic concepts in the systemic drug therapy of breast cancer |
| Abstract: | Optimal management of cancer today requires a thorough and up-to-date understanding of cancer cell kinetics and biochemistry. This report reviews the history and current standards in these fields and how they affect the contemporary approach to breast cancer management. Also outlined are recommended avenues for future research in cytotoxic chemotherapy programs using the principles of cancer cell kinetics as well as the role of newer approaches, including biologic agents such as trastuzumab (Herceptin) and antiangiogenesis agents, in the future therapy of this disease. |
| Keywords: | cancer chemotherapy; unclassified drug; human cell; major clinical study; prednisone; clinical trial; doxorubicin; fluorouracil; dose response; antineoplastic agents; conference paper; paclitaxel; cancer adjuvant therapy; methotrexate; antineoplastic agent; cell division; breast cancer; gene expression; cell growth; antineoplastic combined chemotherapy protocols; drug administration schedule; cyclophosphamide; vincristine; dose-response relationship, drug; breast neoplasms; carmustine; thiotepa; vinblastine; monoclonal antibody; antibodies, monoclonal; multicenter study; cancer cell; receptor, erbb-2; drug cytotoxicity; trastuzumab; granulocyte colony stimulating factor; drug induced disease; bone marrow toxicity; cardiomyopathy; fluoxymesterone; humans; human; female; priority journal |
| Journal Title: | Seminars in Oncology |
| Volume: | 26 |
| Issue: | 1 Suppl. 2 |
| ISSN: | 0093-7754 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1999-02-01 |
| Start Page: | 11 |
| End Page: | 20 |
| Language: | English |
| PUBMED: | 10190780 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Conference Paper -- Export Date: 16 August 2016 -- Source: Scopus |
