Screening and surveillance for colorectal cancer Journal Article


Authors: Markowitz, A. J.; Winawer, S. J.
Article Title: Screening and surveillance for colorectal cancer
Abstract: Colorectal cancer is the second most common cause of cancer death among American men and woman. Currently available screening and surveillance techniques are effective in detecting early-stage colorectal cancer and its premalignant precursor lesion, the adenomatous polyp (adenoma). Removal of adenomas by colonoscopic polypectomy significantly reduces the incidence of colorectal cancer. Appropriate screening and surveillance recommendations should be based on the individual's colorectal cancer risk stratification. High-risk groups, such as patients with hereditary nonpolyposis colorectal cancer (HNPCC) and familial adenomatous polyposis (FAP), should be offered genetic counseling and specialized screening recommendations for colorectal and associated extracolonic malignancies.
Keywords: review; cancer risk; cancer staging; cancer diagnosis; colorectal cancer; risk factors; cancer screening; mass screening; risk factor; cancer mortality; colorectal neoplasms; tumor suppressor gene; colonoscopy; high risk population; genetic screening; polypectomy; cost-benefit analysis; sigmoidoscopy; occult blood; genetic counseling; adenomatous polyp; rectum adenoma; humans; male; female; priority journal; familial polyposis
Journal Title: Seminars in Oncology
Volume: 26
Issue: 5
ISSN: 0093-7754
Publisher: Elsevier Inc.  
Date Published: 1999-10-01
Start Page: 485
End Page: 498
Language: English
PUBMED: 10528896
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 16 August 2016 -- Source: Scopus
Citation Impact
MSK Authors
  1. Arnold J Markowitz
    138 Markowitz
  2. Sidney J Winawer
    274 Winawer