The Simmonds article reviewed [Management of breakthrough pain due to cancer] Journal Article


Author: Manfredi, P.
Article Title: The Simmonds article reviewed [Management of breakthrough pain due to cancer]
Abstract: Breakthrough pain is a complex, multifaceted phenomenon that is an integral part of most cancer pain syndromes and affects the majority of patients with cancer pain. The suggestions listed above are by no means a complete list of the analgesics that physicians may use to treat breakthrough cancer pain. Rather, they are examples of the wide variety of available strategies, and they underscore the need for a comprehensive, individualized, dynamic assessment. Having said all of the above, a fast-and short-acting opioid delivery system that more precisely coincides with the intensity and time course of breakthrough pain episodes, as illustrated by Simmonds' figures, is certainly a good addition to the cancer pain specialist's "bag of tricks." There is good evidence that oral transmucosal fentanyl citrate (Actiq) provides rapid pain relief when compared to placebo.[3] Controlled studies comparing oral transmucosal fentanyl to the usual rescue opioids (eg, morphine, oxycodone, and hydromorphone) will help the practitioner decide whether the higher cost of transmucosal fentanyl is offset by its more rapid onset and more effective analgesia.
Journal Title: Oncology (Norwalk)
Volume: 13
Issue: 8
ISSN: 0890-9091
Publisher: C M P Medica LLC * The Oncology Group  
Date Published: 1999-08-01
Start Page: 1113
End Page: 1114
Language: English
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 16 August 2016 -- Source: Scopus