Potential clinical impact of laser-accelerated beams in cancer ion therapy Conference Paper
| Author: | Obcemea, C. |
| Title: | Potential clinical impact of laser-accelerated beams in cancer ion therapy |
| Conference Title: | 2nd European Advanced Accelerator Concepts Workshop (EAAC 2015) |
| Abstract: | In this article, I present three advantages of plasma-accelerated ion beams for cancer therapy. I discuss how: 1. low-emittance and well-collimated beams are advantageous in proximal normal tissue-sparing; 2. highly-peaked quasi-monoenergetic beams are ideal for fast energy selection and switching in Pencil Beam Scanning (PBS) as a treatment delivery; 3. high fluence and ultra-short pulse delivery produce collective excitations in the medium and enhance the stopping power. This in turn produces denser ionization track signatures (spurs, blobs, etc.) in target tumors, higher linear energy transfer, higher Bragg peak, and higher radiobiological effectiveness at the micro-level. (C) 2016 Elsevier B.V. All rights reserved. |
| Keywords: | clusters; therapy; carbon; proton; hydrogen; radiation-therapy; solids; laser accelerators; stopping power; vicinage effect; cancer ion; energy-loss; track-structure; thin; foils |
| Journal Title | Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment |
| Volume: | 829 |
| Conference Dates: | 2015 12-19 Sep |
| Conference Location: | La Biodola, Italy |
| ISBN: | 0168-9002 |
| Publisher: | Elsevier Science BV |
| Date Published: | 2016-09-01 |
| Start Page: | 149 |
| End Page: | 152 |
| Language: | English |
| ACCESSION: | WOS:000379144100030 |
| DOI: | 10.1016/j.nima.2016.01.058 |
| PROVIDER: | wos |
| Notes: | Article; Proceedings Paper -- 2nd Workshop on European Advanced Accelerator Concepts (EAAC) -- 2015 -- INFN, ITALY -- Source: Wos |
