Hematopoietic cell transplantation for multiple myeloma Book Section
| Authors: | Krishnan, A.; Giralt, S. A. |
| Editors: | Forman, S. J.; Negrin, R. S.; Antin, J. H.; Appelbaum, F. R. |
| Article/Chapter Title: | Hematopoietic cell transplantation for multiple myeloma |
| Abstract: | Myelodysplastic syndromes (MDSs) and myeloproliferative neoplasms (MPNs) are clonal disorders of hematopoietic stem/precursor cells. The only treatment modality with proven curative potential is hematopoietic cell transplantation. Some patients have been followed now in unmaintained remission for more than 25 years. The development of reduced-intensity regimens has allowed us to transplant even patients in their 70s and those with comorbid conditions. However, relapse has remained a major issue, particularly in patients with MDS, largely dependent upon cytogenetic abnormalities. Additional interventions must be designed to prevent or effectively treat relapse. © 2016 John Wiley & Sons, Ltd. All rights reserved. |
| Keywords: | disease classification; relapse; cytogenetics; myelodysplastic syndromes; myeloproliferative neoplasms; comorbidities; post-transplant prognosis |
| Book Title: | Thomas’ Hematopoietic Cell Transplantation: Stem Cell Transplantation. 5th ed |
| Volume: | 1 |
| ISBN: | 978-1-118-41600-6 |
| Publisher: | Wiley Blackwell |
| Publication Place: | Chichester, UK |
| Date Published: | 2016-01-01 |
| Start Page: | 625 |
| End Page: | 639 |
| Language: | English |
| DOI: | 10.1002/9781118416426.ch55 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book Chapter: 55 -- Export Date: 1 September 2016 -- Source: Scopus |
