The CRISPR revolution and its impact on cancer research Journal Article
| Authors: | Kannan, R.; Ventura, A. |
| Article Title: | The CRISPR revolution and its impact on cancer research |
| Abstract: | A revolution in cancer research is underway. Spurred by the advent of the CRISPR-Cas9 technology, new methods to probe the mammalian genomes are being developed. By providing simple, flexible, and cost-effective ways to edit and manipulate the genome of somatic cells of adult animals, these new methods present the opportunity to model cancer progression in vivo with an unprecedented degree of sophistication. Here we provide a brief overview of this exciting and fast-moving field. © 2015, EMH Swiss Medical Publishers Ltd. All rights reserved. |
| Keywords: | cancer research; genome; mouse models; mouse model; cancer; crispr; genome editing; clustered regularly interspaced short palindromic repeat |
| Journal Title: | Swiss Medical Weekly |
| Volume: | 145 |
| ISSN: | 1424-7860 |
| Publisher: | E M H Swiss Medical Publishers Ltd |
| Date Published: | 2015-12-10 |
| Start Page: | w14230 |
| Language: | English |
| DOI: | 10.4414/smw.2015.14230 |
| PROVIDER: | scopus |
| PUBMED: | 26661454 |
| PMCID: | PMC5512432 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 1 September 2016 -- Source: Scopus |
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