Authors: | Glunz, P. W.; He, L.; Horwitz, S. B.; Chakravarty, S.; Ojima, I.; Chou, T. C.; Danishefsky, S. J. |
Article Title: | The synthesis and evaluation of 12,13-benzodesoxyepothilone B: A highly convergent route |
Abstract: | The title compound retains some of the affinity for microtubule assemblies as does 12,13-desoxyepothilone B. |
Keywords: | binding affinity; drug structure; drug synthesis; structure activity relation; microtubule assembly; pharmacophore; structure analysis; molecular model; epothilone a; epothilone b; iodine; paclitaxel derivative; bromine derivative; drug analog; bromide; article |
Journal Title: | Tetrahedron Letters |
Volume: | 40 |
Issue: | 38 |
ISSN: | 0040-4039 |
Publisher: | Pergamon-Elsevier Science Ltd |
Date Published: | 1999-09-17 |
Start Page: | 6895 |
End Page: | 6898 |
Language: | English |
DOI: | 10.1016/s0040-4039(99)01433-1 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Article -- Export Date: 16 August 2016 -- Source: Scopus |