The synthesis and evaluation of 12,13-benzodesoxyepothilone B: A highly convergent route Journal Article


Authors: Glunz, P. W.; He, L.; Horwitz, S. B.; Chakravarty, S.; Ojima, I.; Chou, T. C.; Danishefsky, S. J.
Article Title: The synthesis and evaluation of 12,13-benzodesoxyepothilone B: A highly convergent route
Abstract: The title compound retains some of the affinity for microtubule assemblies as does 12,13-desoxyepothilone B.
Keywords: binding affinity; drug structure; drug synthesis; structure activity relation; microtubule assembly; pharmacophore; structure analysis; molecular model; epothilone a; epothilone b; iodine; paclitaxel derivative; bromine derivative; drug analog; bromide; article
Journal Title: Tetrahedron Letters
Volume: 40
Issue: 38
ISSN: 0040-4039
Publisher: Pergamon-Elsevier Science Ltd  
Date Published: 1999-09-17
Start Page: 6895
End Page: 6898
Language: English
DOI: 10.1016/s0040-4039(99)01433-1
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 16 August 2016 -- Source: Scopus
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  1. Peter W Glunz
    11 Glunz
  2. Ting-Chao Chou
    319 Chou