Hepatocellular carcinoma: MR imaging findings in cirrhotic livers and noncirrhotic livers Journal Article
| Authors: | Winston, C. B.; Schwartz, L. H.; Fong, Y.; Blumgart, L. H.; Panicek, D. M. |
| Article Title: | Hepatocellular carcinoma: MR imaging findings in cirrhotic livers and noncirrhotic livers |
| Abstract: | PURPOSE: To compare the magnetic resonance (MR) imaging findings of primary hepatocellular carcinoma (HCC) in cirrhotic versus noncirrhotic livers. MATERIALS AND METHODS: MR images in 36 patients with HCC (30 men and six women aged 42-84 years [mean age, 65 years]) were retrospectively reviewed. The number and size of hepatic lesions were assessed. Lesion margins were categorized as well circumscribed or ill defined. The presence of a capsule, intratumoral high signal intensity on T1-weighted MR images, and a stellate scar were determined. RESULTS: Eleven (31%) patients had MR imaging evidence of cirrhosis, and 25 (69%) did not. Lesions in cirrhotic livers differed significantly for those in noncirrhotic livers in terms of size (22 cm2 vs 99 cm2, P < .05), frequency of a solitary lesion (27% vs 72%), P < .05), and frequency of a central scar (6% vs 50%, P < .05). There was no difference between the cirrhotic and noncirrhotic livers with regard to tumor margin, intratumoral high signal intensity on T1-weighted images, or tumor capsule. CONCLUSION: Differences exist in the MR imaging appearance of HCC between patients with and those without cirrhosis, although there is overlap of imaging findings. |
| Keywords: | adult; clinical article; human tissue; aged; aged, 80 and over; middle aged; human cell; histopathology; liver cell carcinoma; liver cirrhosis; carcinoma, hepatocellular; liver neoplasms; nuclear magnetic resonance imaging; magnetic resonance imaging; prevalence; liver; diagnostic value; intermethod comparison; signal processing; quantitative diagnosis; humans; human; male; female; priority journal; article; liver, cirrhosis; liver, mr |
| Journal Title: | Radiology |
| Volume: | 210 |
| Issue: | 1 |
| ISSN: | 0033-8419 |
| Publisher: | Radiological Society of North America, Inc. |
| Date Published: | 1999-01-01 |
| Start Page: | 75 |
| End Page: | 79 |
| Language: | English |
| PUBMED: | 9885590 |
| PROVIDER: | scopus |
| DOI: | 10.1148/radiology.210.1.r99ja1975 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 16 August 2016 -- Source: Scopus |
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