Brain mapping in sedated infants and young children with passive- Functional magnetic resonance imaging Journal Article


Authors: Souweidane, M. M.; Kimb, K. H. S.; McDowall, R.; Ruge, M. I.; Lis, E.; Krol, G.; Hirsch, J.
Article Title: Brain mapping in sedated infants and young children with passive- Functional magnetic resonance imaging
Abstract: Functional magnetic resonance imaging (fMRI) in pediatric patients presents a unique set of problems due to the need for patient compliance, the frequent need for sedation and an early developmental status. A new method for using fMRI in sedated infants and young children is presented using passive stimuli focused on visual, sensorimotor and language functions. All of these stimuli are presented such that no patient interaction is required. Eight sedated children undergoing diagnostic MRI scans of the brain participated in these passive fMRI procedures. Cortical regions were identified using standard techniques applied to the blood-oxygen-level- dependent signal which is the basis for fMRI. The results support the feasibility of brain mapping in sedated children with passive fMRI techniques.
Keywords: clinical article; preschool child; school child; nuclear magnetic resonance imaging; brain tumor; preoperative evaluation; propofol; diagnostic imaging; feasibility study; infant; vision; fmri; language; brain mapping; sensorimotor function; human; priority journal; article; pediatric anesthesia; cortical mapping; passive stimulation
Journal Title: Pediatric Neurosurgery
Volume: 30
Issue: 2
ISSN: 1016-2291
Publisher: Karger  
Date Published: 1999-02-01
Start Page: 86
End Page: 92
Language: English
DOI: 10.1159/000028768
PUBMED: 10325564
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 16 August 2016 -- Source: Scopus
Altmetric Score
MSK Authors
  1. Eric Lis
    104 Lis
  2. Joy Hirsch
    49 Hirsch
  3. George Krol
    33 Krol
  4. Maximilian I Ruge
    11 Ruge