Technologies of image guidance and the development of advanced linear accelerator systems for radiotherapy Journal Article


Authors: Wu, V. W. C.; Law, M. Y. Y.; Star-Lack, J.; Cheung, F. W. K.; Ling, C. C.
Article Title: Technologies of image guidance and the development of advanced linear accelerator systems for radiotherapy
Abstract: As advanced radiotherapy approaches for targeting the tumor and sparing the normal tissues have been developed, the image guidance of therapy has become essential to directing and confirming treatment accuracy. To approach these goals, image guidance devices now include kV on-board imagers, kV/MV cone-beam CT systems, CT-on-rails, and mobile and in-room radiographic/fluoroscopic systems. Nonionizing sources, such as ultrasound and optical systems, and electromagnetic devices have been introduced to monitor or track the patient and/or tumor positions during treatment. In addition, devices have been designed specifically for monitoring and/or controlling respiratory motion. Optimally, image-guided radiation therapy systems should possess 3 essential elements: (1) 3D imaging of soft tissues and tumors, (2) efficient acquisition and comparison of the 3D images, and (3) an efficacious process for clinically meaningful intervention. Understanding and using these tools effectively is central to current radiotherapy practice. The implementation and integration of these devices continue to carry practical challenges, which emphasize the need for further development of the technologies and their clinical applications. Copyright © 2011 S. Karger AG, Basel.
Keywords: intensity modulated radiation therapy; validation process; cancer radiotherapy; radiation dose; image analysis; breast; diagnostic imaging; imaging system; mammography; algorithm; dosimetry; radiation dose fractionation; image quality; three dimensional imaging; echography; radiography; artifact; image guidance; electromagnetic field; motion; computer program; linear accelerator; cost benefit analysis; image reconstruction; measurement error; cone beam computed tomography; cyberknife; fluoroscopy; breathing mechanics; computed tomography scanner; noise reduction; digital imaging; spiral computer assisted tomography; digital tomosynthesis; image guided radiation therapy; telecommunication
Journal Title: Frontiers of Radiation Therapy and Oncology
Volume: 43
ISSN: 0071-9676
Publisher: S. Karger AG  
Date Published: 2011-01-01
Start Page: 132
End Page: 164
Language: English
DOI: 10.1159/000322414
PROVIDER: scopus
PUBMED: 21625152
DOI/URL:
Notes: Chapter in "IMRT, IGRT, SBRT: Advances in the Treatment Planning and Delivery of Radiotherapy. 2nd ed" (ISBN: 978-3-8055-9680-0) -- "Export Date: 17 August 2011" - "Source: Scopus"
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  1. C Clifton Ling
    331 Ling