Neurologic complications of ovarian carcinoma Journal Article
| Authors: | Abrey, L. E.; Dalmau, J. O. |
| Article Title: | Neurologic complications of ovarian carcinoma |
| Abstract: | BACKGROUND. Neurologic complications of ovarian carcinoma are uncommon and to the authors' knowledge the full spectrum has not been delineated previously. METHODS. The authors reviewed the findings of 121 neurologic consultations on 83 ovarian carcinoma patients between 1993 and 1996; this represents 4% of all ovarian carcinoma patients seen at the study institution in this time period. RESULTS. The most common reasons for consultation were altered mental status, pain, weakness, numbness, headache, and seizure. Twenty-seven consultations diagnosed metastatic disease, 14 diagnosed cerebrovascular disease, and 4 diagnosed paraneoplastic syndromes; however, iatrogenic complications (n = 38) comprised the majority of diagnoses. Greater than 50% of patients improved neurologically after diagnosis and treatment. CONCLUSIONS. Neurologic disease accompanying ovarian carcinoma may be more common and more diverse than recognized previously. Definitive neurologic diagnosis and treatment benefits the majority of patients. |
| Keywords: | adolescent; adult; aged; aged, 80 and over; middle aged; major clinical study; treatment planning; follow up; diagnostic accuracy; ovarian neoplasms; disease association; metastasis; brain; diagnostic value; syndrome; cerebrovascular disease; ovary carcinoma; brain metastasis; paraneoplastic syndrome; mental health; iatrogenic disease; institutional care; nervous system neoplasms; nervous system diseases; cerebrovascular disorders; paraneoplastic syndromes; paraneoplastic; humans; human; female; priority journal; article |
| Journal Title: | Cancer |
| Volume: | 85 |
| Issue: | 1 |
| ISSN: | 0008-543X |
| Publisher: | Wiley Blackwell |
| Date Published: | 1999-01-01 |
| Start Page: | 127 |
| End Page: | 133 |
| Language: | English |
| DOI: | 10.1002/(sici)1097-0142(19990101)85:1<127::aid-cncr18>3.0.co;2-7 |
| PUBMED: | 9921984 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Presented in part at the 122nd Annual Meeting of the American Neurological Association that took place September 28-October 1, 1997 in San Diego, CA -- Export Date: 16 August 2016 -- Source: Scopus |
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