Authors: | von Mehren, M.; Randall, R. L.; Benjamin, R. S.; Boles, S.; Bui, M. M.; Conrad, E. U.; Ganjoo, K. N.; George, S.; Gonzalez, R. J.; Heslin, M. J.; Kane, J. M.; Koon, H.; Mayerson, J.; McCarter, M.; McGarry, S. V.; Meyer, C.; O'Donnell, R. J.; Pappo, A. S.; Paz, I. B.; Petersen, I. A.; Pfeifer, J. D.; Riedel, R. F.; Schuetze, S.; Schupak, K. D.; Schwartz, H. S.; Tap, W. D.; Wayne, J. D.; Bergman, M. A.; Scavone, J. |
Article Title: | Soft Tissue Sarcoma, Version 2.2016 Clinical Practice Guidelines in Oncology |
Abstract: | Soft tissue sarcomas (STS) are rare solid tumors of mesenchymal cell origin that display a heterogenous mix of clinical and pathologic characteristics. STS can develop from fat, muscle, nerves, blood vessels, and other connective tissues. The evaluation and treatment of patients with STS requires a multidisciplinary team with demonstrated expertise in the management of these tumors. The complete NCCN Guidelines for Soft Tissue Sarcoma (available at NCCN.org) provide recommendations for the diagnosis, evaluation, and treatment of extremity/superficial trunk/head and neck STS, as well as intra-abdominal/retroperitoneal STS, gastrointestinal stromal tumor, desmoid tumors, and rhabdomyosarcoma. This manuscript discusses guiding principles for the diagnosis and staging of STS and evidence for treatment modalities that include surgery, radiation, chemoradiation, chemotherapy, and targeted therapy. |
Keywords: | gastrointestinal stromal tumors; solitary fibrous tumor; children; phase-ii trial; refractory solid tumors; polyposis; lymph-node metastasis; cancer-centers-sarcoma; familial adenomatous; previously untreated; diagnosed metastatic rhabdomyosarcoma; line p53 mutations |
Journal Title: | Journal of the National Comprehensive Cancer Network |
Volume: | 14 |
Issue: | 6 |
ISSN: | 1540-1405 |
Publisher: | Harborside Press |
Date Published: | 2016-06-01 |
Start Page: | 758 |
End Page: | 786 |
Language: | English |
ACCESSION: | WOS:000377690100009 |
PROVIDER: | wos |
PUBMED: | 27283169 |
DOI: | 10.6004/jnccn.2016.0078 |
Notes: | Article -- Source: Wos |