Compressive sensing in reflectance confocal microscopy of skin images: A preliminary comparative study Conference Paper

Authors: Arias, F. X.; Sierra, H.; Rajadhyaksha, M.; Arzuaga, E.
Title: Compressive sensing in reflectance confocal microscopy of skin images: A preliminary comparative study
Conference Title: Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXIII
Abstract: Compressive Sensing (CS)-based technologies have shown potential to improve the efficiency of acquisition, manipulation, analysis and storage processes on signals and imagery with slight discernible loss in data performance. The CS framework relies on the reconstruction of signals that are presumed sparse in some domain, from a significantly small data collection of linear projections of the signal of interest. As a result, a solution to the underdetermined linear system resulting from this paradigm makes it possible to estimate the original signal with high accuracy. One common approach to solve the linear system is based on methods that minimize the L1-norm. Several fast algorithms have been developed for this purpose. This paper presents a study on the use of CS in high-resolution reflectance confocal microscopy (RCM) images of the skin. RCM offers a cell resolution level similar to that used in histology to identify cellular patterns for diagnosis of skin diseases. However, imaging of large areas (required for effective clinical evaluation) at such high-resolution can turn image capturing, processing and storage processes into a time consuming procedure, which may pose a limitation for use in clinical settings. We present an analysis on the compression ratio that may allow for a simpler capturing approach while reconstructing the required cellular resolution for clinical use. We provide a comparative study in compressive sensing and estimate its effectiveness in terms of compression ratio vs. image reconstruction accuracy. Preliminary results show that by using as little as 25% of the original number of samples, cellular resolution may be reconstructed with high accuracy. © 2016 SPIE.
Keywords: image acquisition; confocal microscopy; diagnosis; clinical evaluation; image processing; reflectance confocal microscopies; reflection; dermatology; image reconstruction; optimization; optical imaging; non-invasive imaging; compressed sensing; signal reconstruction; digital storage; compressive sensing; biomedical signal processing; re ectance confocal microscopy; linear systems; image reconstruction accuracies; time-consuming procedure; underdetermined linear systems
Journal Title Proceedings of SPIE
Volume: 9713
ISBN: 0277-786X
Publisher: SPIE  
Date Published: 2016-01-01
Start Page: 97130Z
Language: English
DOI: 10.1117/12.2213685
PROVIDER: scopus
Notes: Conference Paper -- Conference code: 122481 -- Export Date: 2 August 2016 -- The Society of Photo-Optical Instrumentation Engineers (SPIE) -- 15 February 2016 through 17 February 2016 -- Source: Scopus
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