Discussions of life expectancy and changes in illness understanding in patients with advanced cancer Journal Article


Authors: Epstein, A. S.; Prigerson, H. G.; O'Reilly, E. M.; Maciejewski, P. K.
Article Title: Discussions of life expectancy and changes in illness understanding in patients with advanced cancer
Abstract: Purpose: Accurate illness understanding enables patients to make informed decisions. Evidence of the influence of prognostic discussions on the accuracy of illness understanding by patients would demonstrate the value of discussions. Methods: Recent and past oncology provider-patient discussions about prognosis/life expectancy were examined for their association with changes in illness understanding by patients. Patients (N = 178) with advanced cancers refractory to prior chemotherapy whom oncologists expected to die within 6 months were interviewed before and after a visit in which cancer restaging scan results were discussed. Illness understanding scores were the sum of four indicator variables: patient terminal illness acknowledgment, recognition of incurable disease status, knowledge of the advanced stage of the disease, and expectation to live months as opposed to years. Results: Before the restaging scan visit, nine (5%) of 178 patients had completely accurate illness understanding (ie, correctly answered each of the four illness understanding questions). Eighteen patients (10%) reported only recent discussions of prognosis/life expectancy with their oncologists; 68 (38%) reported only past discussions; 24 (13%) reported both recent and past discussions; and 68 (38%) reported that they never had discussions of prognosis/life expectancy with their oncologists. After adjustment for potential confounders (ie, education and race/ethnicity), analysis identified significant, positive changes in illness understanding scores for patients in groups that reported recent only (least-squares mean change score, 0.62; 95% CI, 0.23 to 1.01; P = .002) and both recent and past (least-squares mean change score, 0.37; 95% CI, 0.04 to 0.70; P = 0.028) discussions of prognosis/life expectancy with their oncologists. Conclusion: Patients with advanced cancer who report recent discussions of prognosis/life expectancy with their oncologists come to have a better understanding of the terminal nature of their illnesses. © 2016 by American Society of Clinical Oncology.
Journal Title: Journal of Clinical Oncology
Volume: 34
Issue: 20
ISSN: 0732-183X
Publisher: American Society of Clinical Oncology  
Date Published: 2016-07-10
Start Page: 2398
End Page: 2403
Language: English
DOI: 10.1200/jco.2015.63.6696
PROVIDER: scopus
PUBMED: 27217454
PMCID: PMC4981977
DOI/URL:
Notes: Article -- Presented in abstract form at the 51st Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, IL that took place May 29-June 2, 2015, and at the ASCO Palliative Care in Oncology Symposium in Boston, MA on October 9-10, 2015 -- Export Date: 2 August 2016 -- Source: Scopus
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  1. Andrew Saul Epstein
    68 Epstein
  2. Eileen O'Reilly
    306 O'Reilly