Fertility issues in adolescent and young adult cancer survivors Journal Article


Authors: Benedict, C.; Shuk, E.; Ford, J. S.
Article Title: Fertility issues in adolescent and young adult cancer survivors
Abstract: Purpose: Many adolescent and young adult (AYA) cancer survivors place great importance on fertility. This study explored AYAs' discussions of fertility in the context of discussing their survivorship experiences. Methods: Secondary analyses of a qualitative study of young adult survivors of adolescent cancers (AYA survivors) was performed using semistructured individual interviews and focus groups. Analyses were conducted using grounded theory using thematic content analysis with an inductive data-driven approach. Results: Participants (n = 43) were 16-24 years old, diagnosed with cancer between ages 14 and 18 years, and were at least 6 months post-treatment. Before treatment, 5 males banked sperm and no females preserved fertility. More males (50%) than females (39%) reported uncertainty about their fertility. Three major categories emerged from the data: fertility concerns, emotions raised when discussing fertility, and strategies used to manage fertility concerns. Fertility concerns focused on dating/partner reactions, health risks, and what potential infertility would mean for their life narrative. Emotions included distress, feeling overwhelmed and hopeful/wishful thinking. Females were more likely to feel distressed and overwhelmed than males. Strategies to manage concerns included acceptance/making do, desire to postpone concerns, and reliance on assisted reproductive technology. Conclusions: Most AYAs in our study reported a number of reproductive concerns and fertility-related distress after treatment, which may affect other areas of psychosocial functioning. Females may be more at-risk for distress than males, particularly in situations of uncertainty and limited knowledge. Future work should explore how to best incorporate fertility-related informational and support services more fully into survivorship care. Implications for survivorship care are discussed. © Copyright 2016, Mary Ann Liebert, Inc. 2016.
Keywords: adolescent; adult; cancer chemotherapy; clinical article; controlled study; leukemia; cancer surgery; young adult; pancreas cancer; follow up; melanoma; ovary cancer; germ cell; central nervous system tumor; infertility; cancer survivor; sarcoma; cancer center; neuroblastoma; lymphoma; survivorship; emotion; interview; sex difference; thyroid cancer; craniopharyngioma; fertility; qualitative research; ethnicity; sexual behavior; peer group; fertility preservation; content analysis; grounded theory; sperm banking; human; male; female; priority journal; article
Journal Title: Journal of Adolescent and Young Adult Oncology
Volume: 5
Issue: 1
ISSN: 2156-5333
Publisher: Mary Ann Liebert, Inc  
Date Published: 2016-03-01
Start Page: 48
End Page: 57
Language: English
DOI: 10.1089/jayao.2015.0024
PROVIDER: scopus
PMCID: PMC4779291
PUBMED: 26812452
DOI/URL:
Notes: Article -- Preliminary findings of the data were previously presented at the 36th Annual Meeting and Scientific Sessions of the Society of Behavioral Medicine in San Antonio, TX on April 20, 2015, and published as an abstract in the Annual Meeting Supplement issue of the Annals of Behavioral Medicine in April 2015 -- Export Date: 2 August 2016 -- Source: Scopus
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MSK Authors
  1. Jennifer S Ford
    58 Ford
  2. Elyse Shuk
    51 Shuk