Detection of the mcr-1 colistin resistance gene in carbapenem-resistant Enterobacteriaceae from different hospitals in China Journal Article
| Authors: | Yu, H.; Qu, F.; Shan, B.; Huang, B.; Jia, W.; Chen, C.; Li, A.; Miao, M.; Zhang, X.; Bao, C.; Xu, Y.; Chavda, K. D.; Tang, Y. W.; Kreiswirth, B. N.; Du, H.; Chen, L. |
| Article Title: | Detection of the mcr-1 colistin resistance gene in carbapenem-resistant Enterobacteriaceae from different hospitals in China |
| Abstract: | The spread of the plasmid-mediated colistin resistance gene, mcr-1, into carbapenem-resistant Enterobacteriaceae (CRE) clinical isolates poses a significant threat to global health. Here we report the identification of three mcr-1-harboring carbapenem-resistant Escherichia coli strains, collected from three patients in two provinces in China. Our results show that mcr-1-harboring CRE strains have started to spread in different hospitals in China. In addition, this report presents the first description of chromosomal integration of mcr-1 into a carbapenem-resistant E. coli strain. Copyright © 2016, American Society for Microbiology. All Rights Reserved. |
| Journal Title: | Antimicrobial Agents and Chemotherapy |
| Volume: | 60 |
| Issue: | 8 |
| ISSN: | 0066-4804 |
| Publisher: | American Society for Microbiology |
| Date Published: | 2016-08-01 |
| Start Page: | 5033 |
| End Page: | 5035 |
| Language: | English |
| DOI: | 10.1128/aac.00440-16 |
| PROVIDER: | scopus |
| PMCID: | PMC4958199 |
| PUBMED: | 27216058 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 2 August 2016 -- Source: Scopus |
