Classification and regression tree uncovered hierarchy of psychosocial determinants underlying quality-of-life response shift in HIV/AIDS Journal Article


Authors: Li, Y.; Rapkin, B.
Article Title: Classification and regression tree uncovered hierarchy of psychosocial determinants underlying quality-of-life response shift in HIV/AIDS
Abstract: Objectives: Rapkin and Schwartz define response shift as otherwise unexplained, discrepant change in health-related quality of life (HRQOL) that is associated with change in cognitive appraisal. In this article, we demonstrate how a recursive partitioning (rpart) regression tree analytic approach may be used to explore cognitive changes to gain additional insight into response-shift phenomena. Study Design and Setting: Data are from the "Choices in Care Study," an evaluation of HIV+ Medicaid recipients' experiences and outcomes in care (N = 394). Cognitive assessment was based on the QOL appraisal battery. HRQOL was measured by the SF-36 Health Survey, version 2 (SF-36v2). Results: We used rpart to examine 6-month change in SF-36v2 mental composite score as a function of changes in appraisal, after controlling for patient characteristics, health changes, and intervening events. Rpart identified nine distinct patterns of cognitive change, including three associated with negative discrepancies, four with positive discrepancies, and two with no discrepancies. Conclusion: Rpart classification provides a nuanced treatment of response shift. This methodology has implications for evaluating programs, guiding decisions, and targeting care. © 2009 Elsevier Inc. All rights reserved.
Keywords: adult; middle aged; major clinical study; human immunodeficiency virus infection; outcome assessment; quality of life; attitude to health; medicaid; patient care; health status; epidemiologic methods; cognition; psychosocial care; acquired immune deficiency syndrome; health-related quality of life; short form 36; decision making; hiv infections; classification and regression trees; idiographic quality of life assessment; response shift; rpart; segmentation strategies; goals; health status indicators; psychometrics
Journal Title: Journal of Clinical Epidemiology
Volume: 62
Issue: 11
ISSN: 0895-4356
Publisher: Elsevier Inc.  
Date Published: 2009-11-01
Start Page: 1138
End Page: 1147
Language: English
DOI: 10.1016/j.jclinepi.2009.03.021
PUBMED: 19595576
PROVIDER: scopus
PMCID: PMC2754600
DOI/URL:
Notes: --- - "Cited By (since 1996): 4" - "Export Date: 30 November 2010" - "CODEN: JCEPE" - "Source: Scopus"
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  1. Yuelin Li
    219 Li