NCCN Guidelines® Insights: Non-small cell lung cancer, version 4.2016 Journal Article


Authors: Ettinger, D. S.; Wood, D. E.; Akerley, W.; Bazhenova, L. A.; Borghaei, H.; Camidge, D. R.; Cheney, R. T.; Chirieac, L. R.; D'Amico, T. A.; Dilling, T. J.; Dobelbower, M. C.; Govindan, R.; Hennon, M.; Horn, L.; Jahan, T. M.; Komaki, R.; Lackner, R. P.; Lanuti, M.; Lilenbaum, R.; Lin, J.; Loo, B. W.; Martins, R.; Otterson, G. A.; Patel, J. D.; Pisters, K. M.; Reckamp, K.; Riely, G. J.; Schild, S. E.; Shapiro, T. A.; Sharma, N.; Stevenson, J.; Swanson, S. J.; Tauer, K.; Yang, S. C.; Gregory, K.; Hughes, M.
Article Title: NCCN Guidelines® Insights: Non-small cell lung cancer, version 4.2016
Abstract: These NCCN Guidelines Insights focus on recent updates in the 2016 NCCN Guidelines for Non-Small Cell Lung Cancer (NSCLC; Versions 1-4). These NCCN Guidelines Insights will discuss new immunotherapeutic agents, such as nivolumab and pembrolizumab, for patients with metastatic NSCLC. For the 2016 update, the NCCN panel recommends immune checkpoint inhibitors as preferred agents (in the absence of contraindications) for second-line and beyond (subsequent) therapy in patients with metastatic NSCLC (both squamous and nonsquamous histologies). Nivolumab and pembrolizumab are preferred based on improved overall survival rates, higher response rates, longer duration of response, and fewer adverse events when compared with docetaxel therapy.
Journal Title: Journal of the National Comprehensive Cancer Network
Volume: 14
Issue: 3
ISSN: 1540-1405
Publisher: Harborside Press  
Date Published: 2016-03-01
Start Page: 255
End Page: 264
Language: English
PROVIDER: scopus
PUBMED: 26957612
DOI/URL:
Notes: Review -- Export Date: 2 May 2016 -- Source: Scopus
Citation Impact
MSK Authors
  1. Gregory J Riely
    605 Riely