Genomic characterization of Enterobacter cloacae isolates from China that coproduce KPC-3 and NDM-1 carbapenemases Journal Article
| Authors: | Du, H.; Chen, L.; Chavda, K. D.; Pandey, R.; Zhang, H.; Xie, X.; Tang, Y. W.; Kreiswirth, B. N. |
| Article Title: | Genomic characterization of Enterobacter cloacae isolates from China that coproduce KPC-3 and NDM-1 carbapenemases |
| Abstract: | Here, we report two Enterobacter cloacae sequence type 231 isolates coproducing KPC-3 and NDM-1 that have caused lethal infections in a tertiary hospital in China. The blaNDM-1-harboring plasmids carry IncA/C2 and IncR replicons, showing a mosaic plasmid structure, and the blaNDM-1 is harbored on a novel class I integron-like element. blaKPC-3 is located on a Tn3-ΔblaTEM-1-blaKPC-3-ΔTn1722 element, flanked by two 9-bp direct-repeat sequences and harbored on an IncX6 plasmid. Copyright © 2016, American Society for Microbiology. |
| Journal Title: | Antimicrobial Agents and Chemotherapy |
| Volume: | 60 |
| Issue: | 4 |
| ISSN: | 0066-4804 |
| Publisher: | American Society for Microbiology |
| Date Published: | 2016-04-01 |
| Start Page: | 2519 |
| End Page: | 2523 |
| Language: | English |
| DOI: | 10.1128/aac.03053-15 |
| PROVIDER: | scopus |
| PMCID: | PMC4808189 |
| PUBMED: | 26787700 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 2 May 2016 -- Source: Scopus |
