Molecular and clinical assessment in the treatment of AIDS Kaposi sarcoma with valproic acid Journal Article
| Authors: | Lechowicz, M.; Dittmer, D. P.; Lee, J. Y.; Krown, S. E.; Wachsman, W.; Aboulafia, D.; Dezube, B. J.; Ratner, L.; Said, J.; Ambinder, R. F. |
| Article Title: | Molecular and clinical assessment in the treatment of AIDS Kaposi sarcoma with valproic acid |
| Abstract: | The AIDS Malignancy Consortium undertook a pilot trial of valproic acid among patients with AIDS-associated Kaposi sarcoma (KS). Treatment was associated with low toxicity, but the KS clinical response and KS herpesvirus lytic induction rates were not sufficiently high to meet predefined criteria for efficacy. © 2009 by the Infectious Diseases Society of America. All rights reserved. |
| Keywords: | adult; treatment response; middle aged; major clinical study; drug efficacy; drug safety; prospective study; prospective studies; patient monitoring; pilot study; acquired immune deficiency syndrome; acquired immunodeficiency syndrome; kaposi sarcoma; sarcoma, kaposi; rna, viral; valproic acid; human herpesvirus 8; herpesvirus 8, human |
| Journal Title: | Clinical Infectious Diseases |
| Volume: | 49 |
| Issue: | 12 |
| ISSN: | 1058-4838 |
| Publisher: | Oxford University Press |
| Date Published: | 2009-12-01 |
| Start Page: | 1946 |
| End Page: | 1949 |
| Language: | English |
| DOI: | 10.1086/648447 |
| PUBMED: | 19911999 |
| PROVIDER: | scopus |
| PMCID: | PMC2952388 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 2" - "Export Date: 30 November 2010" - "CODEN: CIDIE" - "Source: Scopus" |
