Acute and delayed bleeding requiring embolization after image-guided liver biopsy in patients with cancer Journal Article

Authors: Sag, A. A.; Brody, L. A.; Maybody, M.; Erinjeri, J. P.; Wang, X.; Wimmer, T.; Silk, M.; Petre, E. N.; Solomon, S. B.
Article Title: Acute and delayed bleeding requiring embolization after image-guided liver biopsy in patients with cancer
Abstract: Purpose: To report incidence of acute versus delayed presentations of bleeding requiring embolization after focal liver biopsy, in correlation with angiographic findings and treatment success rates. The available literature will be reviewed as well. Materials and methods: Health Insurance Portability and Accountability Act-compliant institutional review board approved retrospective review of 2180 consecutive patients undergoing 2335 targeted liver biopsies at a tertiary-care cancer center. Hepatic arterial embolization episodes within 30 days from biopsy were identified via radiology PACS. Electronic medical record review was performed for indication of embolization and postembolization clinical course. Results: The incidence of postbiopsy bleeding requiring embolization was 0.5% (12/2335 biopsies). In those with bleeding, 1/12 (8%) had no hepatic arterial findings at angiography. Angiographic hepatic arterial findings resolved after embolization in 11/11 patients (100% technical success). Bleeding ceased after embolization in 10/12 patients (83% clinical success). Complications were seen in 2/12 (17%) patients: cholecystitis and hepatic infarct, respectively. Delayed presentation of bleeding (defined as >. 24 h postbiopsy) occurred in 5/12 (42%) patients; the longest latency was 12 days. Conclusion: The overall incidence of bleeding requiring embolization in our population was 0.5%. This complication rate compares favorably to the 0-4.2% (median: 0.29%) rate quoted in the available, heterogeneous, literature on this topic. Delayed presentation occurred in almost half of patients. Arterial embolization carries excellent technical and clinical success rates. © 2015 Elsevier Inc.
Keywords: radiology, interventional; embolization, therapeutic; hemorrhage; image-guided biopsy
Journal Title: Clinical Imaging
Volume: 40
Issue: 3
ISSN: 0899-7071
Publisher: Elsevier Inc.  
Date Published: 2016-05-01
Start Page: 535
End Page: 540
Language: English
DOI: 10.1016/j.clinimag.2015.11.004
PROVIDER: scopus
PUBMED: 27133700
Notes: Article -- Export Date: 4 April 2016 -- Source: Scopus
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MSK Authors
  1. Xiaodong Wang
    4 Wang
  2. Majid Maybody
    73 Maybody
  3. Lynn Brody
    97 Brody
  4. Stephen Solomon
    283 Solomon
  5. Joseph Patrick Erinjeri
    101 Erinjeri
  6. Elena Nadia Petre
    52 Petre
  7. Thomas Wimmer
    6 Wimmer
  8. Mikhail Thomas Silk
    11 Silk
  9. Alan Alper Sag
    4 Sag