Venous thromboembolism after radical cystectomy: Experience with screening ultrasonography Journal Article


Authors: Murray, K. M.; Parker, W.; Stephany, H.; Redger, K.; Mirza, M.; Lopez-Corona, E.; Holzbeierlein, J. M.; Lee, E. K.
Article Title: Venous thromboembolism after radical cystectomy: Experience with screening ultrasonography
Abstract: Objectives To detect the incidence of immediate postoperative deep vein thrombosis (DVT) using screening lower extremity ultrasonography (US) in patients undergoing radical cystectomy (RC) and to determine the rate of symptomatic pulmonary embolism (PE) after RC and identify risk factors for venous thromboembolic (VTE) events in a RC population. Patients and methods We performed a retrospective review of prospective data collected on patients who underwent RC between July 2008 and January 2012. These patients underwent screening US at 2/3 days after RC to determine the rate of asymptomatic DVT. A chart review was completed to identify those who had a symptomatic PE. Univariate and multivariable analysis was used to identify risk factors associated with DVT, PE and total VTE events. Results In all, 221 patients underwent RC and asymptomatic DVT was identified in 21 (9.5%) on screening US. Nine (4.5%) developed symptomatic PE at a median of 9 days, of which no patients had positive lower extremity US postoperatively. Increased length of hospital stay, increased estimated blood loss, and lower body mass index were linked to risk of PE, and only a previous history of DVT was associated with postoperative DVT. Conclusion Patients who undergo RC are at high-risk for thromboembolic events and multimodal prophylaxis should be administered. Clinicians should be especially vigilant in those who demonstrate factors associated with higher risk for VTE events. © 2015 Arab Association of Urology.
Keywords: deep vein thrombosis; pulmonary embolism; radical cystectomy; ultrasonography; venous thromboembolism
Journal Title: Arab Journal of Urology
Volume: 14
Issue: 1
ISSN: 2090-598X
Publisher: Elsevier Inc.  
Date Published: 2016-03-01
Start Page: 37
End Page: 43
Language: English
DOI: 10.1016/j.aju.2015.11.002
PROVIDER: scopus
PMCID: PMC4767786
PUBMED: 26966592
DOI/URL:
Notes: Article -- Export Date: 4 April 2016 -- Source: Scopus
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  1. Katie S Murray
    16 Murray