The Glioma International Case-Control Study: A report from the Genetic Epidemiology of Glioma International Consortium Journal Article

   


Authors: Amirian, E. S.; Armstrong, G. N.; Zhou, R.; Lau, C. C.; Claus, E. B.; Barnholtz-Sloan, J. S.; Il'yasova, D.; Schildkraut, J.; Ali-Osman, F.; Sadetzki, S.; Johansen, C.; Houlston, R. S.; Jenkins, R. B.; Lachance, D.; Olson, S. H.; Bernstein, J. L.; Merrell, R. T.; Wrensch, M. R.; Davis, F. G.; Lai, R.; Shete, S.; Amos, C. I.; Scheurer, M. E.; Aldape, K.; Alafuzoff, I.; Brännström, T.; Broholm, H.; Collins, P.; Giannini, C.; Rosenblum, M.; Tihan, T.; Melin, B. S.; Bondy, M. L.
Article Title: The Glioma International Case-Control Study: A report from the Genetic Epidemiology of Glioma International Consortium
Abstract: Decades of research have established only a few etiological factors for glioma, which is a rare and highly fatal brain cancer. Common methodological challenges among glioma studies include small sample sizes, heterogeneity of tumor subtypes, and retrospective exposure assessment. Here, we briefly describe the Glioma International Case-Control (GICC) Study (recruitment, 2010-2013), a study being conducted by the Genetic Epidemiology of Glioma International Consortium that integrates data from multiple data collection sites, uses a common protocol and questionnaire, and includes biospecimen collection. To our knowledge, the GICC Study is the largest glioma study to date that includes collection of blood samples, which will allow for genetic analysis and interrogation of gene-environment interactions. © 2015 The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved.
Keywords: case-control studies; glioma; methodology; glioblastoma; cancer; study profile
Journal Title: American Journal of Epidemiology
Volume: 183
Issue: 2
ISSN: 0002-9262
Publisher: Oxford University Press  
Date Published: 2016-01-15
Start Page: 85
End Page: 91
Language: English
DOI: 10.1093/aje/kwv235
PROVIDER: scopus
PMCID: PMC4706682
PUBMED: 26656478
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-84960080630&partnerID=40&md5=addf719c51c19ea59cad178d2465a435
Notes: Article -- Export Date: 4 April 2016 -- Source: Scopus
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  1. Sara H Olson
    232 Olson
  2. Marc Rosenblum
    411 Rosenblum
  3. Jonine L Bernstein
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