Use of disinfection cap to reduce central-line-associated bloodstream infection and blood culture contamination among hematology-oncology patients Journal Article
| Authors: | Kamboj, M.; Blair, R.; Bell, N.; Son, C.; Huang, Y. T.; Dowling, M.; Lipitz-Snyderman, A.; Eagan, J.; Sepkowitz, K. |
| Article Title: | Use of disinfection cap to reduce central-line-associated bloodstream infection and blood culture contamination among hematology-oncology patients |
| Abstract: | objective. In this study, we examined the impact of routine use of a passive disinfection cap for catheter hub decontamination in hematology–oncology patients. setting. A tertiary care cancer center in New York City methods. In this multiphase prospective study, we used 2 preintervention phases (P1 and P2) to establish surveillance and baseline rates followed by sequential introduction of disinfection caps on high-risk units (HRUs: hematologic malignancy wards, hematopoietic stem cell transplant units and intensive care units) (P3) and general oncology units (P4). Unit-specific and hospital-wide hospital-acquired central-line– associated bloodstream infection (HA-CLABSI) rates and blood culture contamination (BCC) with coagulase negative staphylococci (CONS) were measured. results. Implementation of a passive disinfection cap resulted in a 34% decrease in hospital-wide HA-CLABSI rates (combined P1 and P2 baseline rate of 2.66–1.75 per 1,000 catheter days at the end of the study period). This reduction occurred only among high-risk patients and not among general oncology patients. In addition, the use of the passive disinfection cap resulted in decreases of 63% (HRUs) and 51% (general oncology units) in blood culture contamination, with an estimated reduction of 242 BCCs with CONS. The reductions in HA-CLABSI and BCC correspond to an estimated annual savings of $3.2 million in direct medical costs. conclusion. Routine use of disinfection caps is associated with decreased HA-CLABSI rates among high-risk hematology oncology patients and a reduction in blood culture contamination among all oncology patients. © 2015 by The Society for Healthcare Epidemiology of America. |
| Keywords: | major clinical study; clinical trial; prospective study; protective clothing; oncology; high risk patient; cost control; health care cost; patient care; bloodstream infection; vancomycin resistant enterococcus; catheter infection; disinfection; blood culture; gram positive bacterium; staphylococcus; human; article; disinfection cap; hospital running cost |
| Journal Title: | Infection Control and Hospital Epidemiology |
| Volume: | 36 |
| Issue: | 12 |
| ISSN: | 0899-823X |
| Publisher: | The Society for Healthcare Epidemiology of America |
| Date Published: | 2015-12-01 |
| Start Page: | 1401 |
| End Page: | 1408 |
| Language: | English |
| DOI: | 10.1017/ice.2015.219 |
| PROVIDER: | scopus |
| PUBMED: | 26394849 |
| PMCID: | PMC4988232 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 4 April 2016 -- Source: Scopus |
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