Novel approaches to thyroid cancer treatment and response assessment Journal Article


Authors: Grewal, R. K.; Ho, A.; Schöder, H.
Article Title: Novel approaches to thyroid cancer treatment and response assessment
Abstract: The incidence of thyroid cancer has been increasing. After total thyroidectomy of well-differentiated thyroid tumors with intermediate- or high-risk features on pathology, radioiodine remains one of the mainstays of therapy for both thyroid remnant ablation as well as for treatment of metastatic disease. SPECT/CT, a relatively new modality, has been shown to play a pivotal role predominantly in the post-therapy setting by changing the risk stratification of patients with thyroid cancer. In the case of radioiodine treatment failure, FDG-PET/CT may provide prognostic information based on extent and intensity of metabolically active metastatic sites as well as serve as an important imaging test for response assessment in patients treated with chemotherapy, targeted therapies, or radiotherapy, thereby affecting patient management in multiple ways. The role of newer redifferentiation drugs has been evaluated with the use of I-124 PET/CT. © 2016 Published by Elsevier Inc.
Journal Title: Seminars in Nuclear Medicine
Volume: 46
Issue: 2
ISSN: 0001-2998
Publisher: Elsevier Inc.  
Date Published: 2016-03-01
Start Page: 109
End Page: 118
Language: English
DOI: 10.1053/j.semnuclmed.2015.10.010
PROVIDER: scopus
PMCID: PMC4761874
PUBMED: 26897715
DOI/URL:
Notes: Article -- Export Date: 3 March 2016 -- Source: Scopus
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  1. Ravinder K Grewal
    82 Grewal
  2. Heiko Schoder
    543 Schoder
  3. Alan Loh Ho
    237 Ho