Abstract: |
Nevi are the strongest risk factor for melanoma, as the risk of melanoma rises in individuals with a high number of melanocytic nevi. Yet, the melanocytic nevi in an individual change throughout one’s lifetime. By definition, acquired nevi appear after birth; the number of acquired nevi increases in the early decades, followed by a decrease in later life. According to the prevailing wisdom, individuals acquire nevi which then senesce and ultimately disappear; however, the process of nevogenesis may, in fact, be more dynamic. Although dermoscopy can provide greater insights into nevogenesis, there are relatively few studies that closely follow the development of nevi over an individual’s lifetime. Cross-sectional and longitudinal studies regarding the dermoscopic pattern of nevi and the number of melanocytic nevi in both children and adults will be discussed below. © Springer-Verlag Berlin Heidelberg 2012. |