Fertility preservation and cancer: Challenges for adolescent and young adult patients Journal Article


Authors: Benedict, C.; Thom, B.; Kelvin, J. F.
Article Title: Fertility preservation and cancer: Challenges for adolescent and young adult patients
Abstract: Purpose of review With increasing survival rates, fertility is an important quality of life concern for many young cancer patients. There is a critical need for improvements in clinical care to ensure patients are well informed about infertility risks and fertility preservation options and to support them in their reproductive decision-making prior to treatment. Recent findings Several barriers prevent fertility from being adequately addressed in the clinical context. Providers' and patients' incomplete or inaccurate understanding of infertility risks exacerbate patients' reproductive concerns. For female patients in particular, making decisions about fertility preservation before treatment often leads to decision conflict, reducing the likelihood of making informed, value-based decisions, and posttreatment regret and distress. Recent empirically based interventions to improve provider training around fertility issues and to support patient decision-making about fertility preservation show promise. Summary Providers should be knowledgeable about the infertility risks associated with cancer therapies and proactively address fertility with all patients who might one day wish to have a child. Comprehensive counseling should also include related issues such as contraceptive use and health implications of early menopause, regardless of desire for future children. Although the negative psychosocial impact of cancer-related infertility is now well accepted, limited work has been done to explore how to improve clinical management of fertility issues in the context of cancer care. Evidence-based interventions should be developed to address barriers and provide psychosocial and decision-making support to patients who are concerned about their fertility and interested in fertility preservation options. Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.
Keywords: infertility; fertility; reproductive health; fertility preservation; cancer
Journal Title: Current Opinion in Supportive and Palliative Care
Volume: 10
Issue: 1
ISSN: 1751-4258
Publisher: Lippincott Williams & Wilkins  
Date Published: 2016-03-01
Start Page: 87
End Page: 94
Language: English
DOI: 10.1097/spc.0000000000000185
PROVIDER: scopus
PMCID: PMC4752165
PUBMED: 26730794
DOI/URL:
Notes: Review -- Export Date: 3 March 2016 -- Source: Scopus
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  1. Bridgette Thom
    95 Thom
  2. Joanne F Kelvin
    92 Kelvin