Recurrence patterns of intraductal papillary mucinous neoplasms of the pancreas on enhanced computed tomography Journal Article

  


Authors: Landa, J.; Allen, P.; D'Angelica, M.; Schwartz, L. H.
Article Title: Recurrence patterns of intraductal papillary mucinous neoplasms of the pancreas on enhanced computed tomography
Abstract: Objective: To characterize imaging features and findings in recurrent intraductal papillary mucinous neoplasms (IPMN); thereby reconciling the "field defect" theory with the appearance of recurrences distant from the resection margin. Methods: Computed tomography findings were reviewed in 89 patients who were resected with IPMN. At follow-up, the appearance of the pancreatic duct, features of recurrent masses, evidence of enhancement, calcifications, lymphadenopathy, and metastases were recorded. Results: Fourteen (16%) of the 89 patients had evidence of recurrence. Nine (64%) of the 14 patients demonstrated evidence for local recurrence. Ten recurrent lesions were noted in 9 patients. Patients with recurrence demonstrated an increase of pancreatic ductal dilatation of 3.3 mm, whereas patients without recurrence either had no dilatation or dilatation which then decreased over time. Conclusions: Computed tomography findings suspicious for tumor recurrence include enlarging mass (either solid, cystic or both), progressive ductal dilatation, or extrapancreatic disease. There was a lack of correlation between margin status and location of recurrence within the pancreas consistent with the global field defect theory of IPMN. Copyright © 2009 by Lippincott Williams & Wilkins.
Keywords: adult; aged; aged, 80 and over; middle aged; retrospective studies; major clinical study; pancreatic neoplasms; follow up; methodology; pancreaticoduodenectomy; pancreas; tumor localization; metastasis; computer assisted tomography; neoplasm recurrence, local; tumor volume; intraductal papillary mucinous tumor; adenocarcinoma, mucinous; carcinoma, papillary; tomography, x-ray computed; pathology; retrospective study; diagnostic agent; computer assisted diagnosis; image enhancement; contrast enhancement; tumor recurrence; pancreas duct; pancreas tumor; iohexol; contrast medium; contrast media; radiography; papillary carcinoma; colloid carcinoma; lymphadenopathy; pancreas disease; computed tomography; field defect theory; recurrent ipmn; calcification; dilatation; theory; radiographic image interpretation, computer-assisted
Journal Title: Journal of Computer Assisted Tomography
Volume: 33
Issue: 6
ISSN: 0363-8715
Publisher: Lippincott Williams & Wilkins  
Date Published: 2009-11-01
Start Page: 838
End Page: 843
Language: English
DOI: 10.1097/RCT.0b013e3181a7e2a8
PUBMED: 19940647
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-73949159484&partnerID=40&md5=93ea5c647c9ec847c126111d486c73da
Notes: --- - "Export Date: 30 November 2010" - "CODEN: JCATD" - "Source: Scopus"
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MSK Authors
  1. Lawrence H Schwartz
    306 Schwartz
  2. Jonathan Landa
    37 Landa
  3. Peter Allen
    501 Allen
  4. Michael D'Angelica
    777 D'Angelica
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